BACKGROUND Auto-regulated inspiratory support mode (ARIS) is an original closed-loop pressure-support system that regulates the slope ("A") and the initial level ("B") of the applied inspiratory pressure, in order to achieve an optimal minute ventilation under constrained respiratory frequency, tidal volume, and maximum inspiratory airway pressure. The servo-controlled design results in a more ...

Obesity impairs peri-operative lung function. To evaluate the impact of pressure support ventilation vs pressure controlled ventilation in moderately obese adults upon early postoperative lung function, we randomly assigned 68 moderately obese patients (body mass index 25-35 kg x m(-2)) undergoing minor surgery to receive intra-operative ventilation either with pressure support or pressure cont...

Mechanically, breath design is usually either flow/volume-targeted or pressure-targeted. Both approaches can effectively provide lung-protective ventilation, but they prioritize different ventilation parameters, so their responses to changing respiratory-system mechanics and patient effort are different. These different response behaviors have advantages and disadvantages that can be important ...

Editor—Lung-protective ventilation (LPV), in which the tidal volume is restricted to 6 ml kg and the plateau pressure to ,30 cm H2O, is the accepted standard of care for patients with acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS). A growing body of evidence supports the implementation of LPV in patients with other forms of acute respiratory failure and even in patie...

1. Savi A, Gasparetto Maccari J, Frederico Tonietto T, Peçanha Antonio AC, Pinheiro de Oliveira R, de Mello Rieder M, Zignani EC, et al. Influence of FIO2 on PaCO2 during noninvasive ventilation in patients with COPD. Respir Care 2014; 59(3):383-387. 2. Lee J, Read J. Effect of oxygen breathing on distribution of pulmonary blood flow in chronic obstructive lung disease. Am Rev Respir Dis 1967;9...

The aim of this prospective randomized, double-blind study was to investigate the effects of pressure controlled and volume controlled ventilation on mucociliary clearance under general anaesthesia maintained with total intravenous anaesthesia. After approval by the Ethics Committee, 60 patients scheduled for tympanoplasty or tympanomasteidectomy under general anaesthesia were enrolled in the s...

Helium-oxygen mixtures and pressure-support ventilation have been used to unload the respiratory muscles and increase exercise tolerance in COPD. Considering the different characteristics of these techniques, we hypothesized that helium-oxygen would be more effective in reducing exercise-induced dynamic hyperinflation than pressure-support. We also hypothesized that patients would experience gr...

background: postoperative pulmonary dysfunction is one of the most frequent complications after cardiac surgery and it is believed to result from the use of cardiopulmonary bypass (cpb). in this study, we investigated the effect of low tidal volume ventilation during cpb on postoperative gas exchange and lung mechanics. methods: this prospective randomized study included 100 patients undergoing...