The cardiovascular effects of a new, long-acting, sympathomimetic amine, Aramine, are described. Cardiac output, aortic pressure, coronary flow, and ventricular stroke work rise while atrial pressures fall. A sustained increase in myocardial contractility is produced and the myocardium does not require more coronary flow per unit of ventricular work after its administration. The circulatory eff...

This work was presented in part at the Annual Meeting of the American College of Physicians, Boston, Mass., April, 1968 (Ann. Intern. Med. 68: 1153). Received for publication 13 February 1969 and in revised form 18 June 1969. usually rose proportionally, with the absolute rise of LVEDP surpassing that of RAP. Although the absolute level of the central venous pressure thus may not be a reliable ...

Multiple modalities contribute to the evaluation of ventricular function. The role of cineangiography, echocardiography, MR imaging, ultrafast CT, and nuclear medicine continue to evolve and improve our understanding of the physiology and pathophysiology of ventricular function. This article discusses the use and limitation of each modality.

mitochondria play an important role in energy production for the cell. the proper function of a myocardial cell largely depends on the functional capacity of the mitochondria.  therefore it is necessary to establish a novel and reliable method for a non-invasive assessment of mitochondrial function and metabolism in humans. although originally designed for evaluating myocardial perfusion, 99mtc...

Pulmonary hypertension (PH) is an important cause of heart failure in chronic obstructive pulmonary disease (COPD). The pro brain natriuretic peptide N-terminal (NT-proBNP) has been suggested as a noninvasive marker to evaluate ventricular function. However, there is no evidence to support the use of NT-proBNP in monitoring the benefits of vasodilators in COPD induced PH. Thus, we used NT-proBN...

background: preeclampsia is a condition observed during pregnancy and threatens the life of both mother and fetus. there are studies which suggest that preeclampsia play a major role in the left ventricular mass. the aim of this study is to compare the electrocardiographic changes in normal pregnant and preeclamptic women. methods: the studied groups consisted of 48 mild preeclamptic, 33 severe...

INTRODUCTION AND OBJECTIVES To evaluate ventricular function using Doppler echocardiography in patients with an atrial septal defect (ASD). METHODS The study involved 158 children, who were divided into two groups: Group 1 comprised 111 children with an ASD, and Group 2, 47 healthy children. Left ventricular systolic function was evaluated by measuring the ejection fraction, the shortening fr...

Mitochondria play an important role in energy production for the cell. The proper function of a myocardial cell largely depends on the functional capacity of the mitochondria.  Therefore it is necessary to establish a novel and reliable method for a non-invasive assessment of mitochondrial function and metabolism in humans. Although originally designed for evaluating myocardial perfusion, 99mTc...