objective(s): first, 10-bromodecanoic acid was covalently attached to all available surface primary amines of ppi g2 and g3 to increase their lipophilicity. in the subsequent step, ppis were conjugated to the alkylcarboxylate groups of alkylcarboxylate-ppi derivatives to increase the number of surface primary amines. physicochemical properties of modified ppis were determined. transfection expe...

human parvovirus b19, the causative agent of fifth disease in childhood, is non-enveloped dna virus and resistant to many physicochemical agents. b19 is a potential risk to hemophiliac patients receiving blood products. to determine the prevalence of the corresponding antibody in patients with hemophilia a or b or von will brand’s disease (vwbd), we tested 180 hemophilia patients aged 1-45 year...

background viral hepatitis is a systemic infection affecting the liver predominantly. almost all cases of acute viral hepatitis are caused by one of five viral agents: hav, hbv, hcv, hdv and hev. the present study aimed to find out the frequency of various forms of viral hepatitis (hav, hbv, and hcv), route of transmission, the history of vaccination against hepatitis b, and clinical findings i...

Background: Viral load and alanine aminotransferase (ALT) levels may not be the key points for making a decision in the treatment of anti-HBe positive chronic hepatitis B. The purpose of this study was to assess the histological evaluation of liver to find the need for treatment on 72 patients with anti-HBe positive chronic hepatitis B. Methods: The liver biopsy slides of the 72 patients (56 s...

An in vitro study was conducted to know the veridical properties of silver nanoparticles synthesized from   locally available white button mushrooms (Agaricus bisporus). The characterized colloidal silver nanoparticles exhibited as an excellent virucidal property on viral strain Bacteriophage. The viral inactivation process was increased with increasing the concentration of colloidal s...

An in vitro study was conducted to know the veridical properties of silver nanoparticles synthesized from   locally available white button mushrooms (Agaricus bisporus). The characterized colloidal silver nanoparticles exhibited as an excellent virucidal property on viral strain Bacteriophage. The viral inactivation process was increased with increasing the concentration of colloidal s...

conclusions more than 40% of the hemophilic patients under 20 years of age in the present study had no immunity against hepatitis a, and 23% of hepatitis c patients had not had a hepatitis a co-infection yet. since hepatitis a can show a fulminant course in hepatitis c patients, vaccination against hepatitis a seems necessary in hemophilic patients in the region. background hemophilic patients ...

800x600 hepatitis b virus (hbv) infection is the main cause of chronic hepatitis, cirrhosis and hepatocellular carcinoma (hcc). several factors such as serum hbv dna level, genotype and specific viral mutations have been clarified to determine disease progression of chronic hepatitis b. among these, mutations can also occur in chronic hbv patients with antiviral treatment such as lamivudine the...

background: viruses are by far the most common cause of meningitis in children. objectives: the aim of this study is to describe the epidemiology of viral/aseptic meningitis (am) in children (2 months - 15 years) in shiraz. materials and methods: this is a cross-sectional prospective-descriptive study from may 2001 to may 2002 in nemazi and dastgheib hospitals, shiraz. ev meningitis was diagnos...