PURPOSE We evaluated the expression of microsatellite instability (MSI) in sporadic ovarian tumors using 5 standard and 9 new MSI markers to determine the clinical significance of MSI in sporadic epithelial ovarian tumors. MATERIALS AND METHODS MSI was examined in 21 borderline and 25 malignant ovarian tumors. Polymerase chain reaction (PCR) was performed using the 5 markers recommended by th...

Introduction: Ovarian tumors have various histomorphological patterns. Histopathological examination plays an important role is classifying ovarian tumors for better prognosis. Ovarian tumors are classified into surface epithelial tumors, germ tumors and sex cord stromal tumors. This study was done to know various histomorphological patterns of ovarian tumors. Materials and Methods: Both retros...

21-hydroxylase deficiency (21-OHD) caused congenital adrenal hyperplasia (CAH) is a group of autosomal recessive genetic disorders resulting from mutations in genes involved with cortisol (CO) synthesis in the adrenal glands. Testicular adrenal rest tumors (TARTs) are rarely the presenting symptoms of CAH. Here, we describe a case of simple virilizing CAH with TARTs, in a 15-year-old boy. The p...

background: ovarian cancer comprises a heterogeneous group of neoplasms. the prognosis cannot be predicted by histopathologic examination alone. the aim of this study is to evaluate p53, pten, and β-catenin expressions in primary ovarian carcinomas in an attempt to find a possible relationship with morphologic parameters and clinical findings. methods: the study included 100 epithelial ovarian ...

21-hydroxylase deficiency (21-ohd) caused congenital adrenal hyperplasia (cah) is a group of autosomal recessive genetic disorders resulting from mutations in genes involved with cortisol (co) synthesis in the adrenal glands. testicular adrenal rest tumors (tarts) are rarely the presenting symptoms of cah. here, we describe a case of simple virilizing cah with tarts, in a 15-year-old boy. the p...

OBJECTIVES Subjective ultrasonographic assessment is currently considered to be the best method of differentiation between various types of ovarian tumors. The aim of the study was to evaluate selected ultrasonographic features and CA125 levels of hormonally active ovarian tumors. MATERIAL AND METHODS A total of 1135 women with ovarian tumors were diagnosed between 2006 and 2014 at the Divisi...

Ovarian steroid cell tumors (SCTs) are a rare type of sex-cord stromal that account for 0.1% all ovarian tumors. These can occur at any age and typically secrete hormones such as androstenedione testosterone. We report young woman with known microprolactinoma who presented secondary amenorrhea virilization was found to have secreting SCT. A 32-year-old nulligravid history infertility evaluation...

Ovarian metastatic tumors represents up to 10% of all ovarian malignancies. The most encountered tumors which may give birth to ovarian cancer are those originating from the gastric tube; however, other malignancies such as breast, cervix, lung or even skin may be associated with ovarian metastatic tumors. This is a literature review of the most frequently seen ovarian metastatic tumors.