Regenerative medicine would be the most exciting area in the recent scientific topics. In the history of human gene therapy, the severe combined immunodeficiency caused by the absence of adenosine deaminase (SCID-ADA) was the first monogenic disorder for which gene therapy was developed in 1990. Over 30 patients have been treated worldwide using the current protocols, and recent trials provided...

Breast cancer has a high risk of metastasis; however, no effective treatment been established. We developed novel immunotherapy for breast to enhance cytotoxic T lymphocytes against cells using N1-type neutrophils with anti-tumor properties. For this purpose, we combined CXCL2 (CXC chemokine ligand 2) plasmid DNA inactivated Sendai virus (hemagglutinating Japan)-envelope (HVJ-E). The combinatio...