Complementary treatment possibilities for the therapy of cancer are increasing in demand due to the severe side effects of the standard cytostatics used in the first-line therapy. A common approach as a complementary treatment is the use of aqueous extracts of Viscum album L. (Santalaceace). The therapeutic activity of these extracts is attributed to Mistletoe lectins which are Ribosome-inactiv...

The hemiparasitic flowering plant Viscum album (European mistletoe) is known for its very special life cycle, extraordinary biochemical properties, and extremely large genome. size of genome estimated to be 30 times larger than the human 600 model Arabidopsis thaliana . To achieve insights into Gene Space genome, which defined as space including surrounding protein-coding regions, a transcripto...

objective: the present study was designed to investigate the analgesic effect of oral and i.p. administration of alcoholic viscum album (v.a) fruit extract as a rich source of alkaloid substances. materials and methods: experimented animals were divided into control and treatment groups. the treatment rats received different doses of the v.a fruit extract, which was prepared from alcoholic sma...

Phytochemical studies on Viscum coloratum have resulted in the isolation of nineteen compounds. The structures of the isolated compounds were identified on the basis of 1D, 2D NMR and HR-ESI-Q-TOF-MS. Pachypodol (4) and ombuine (6) were characterized in the family Loranthaceae for the first time. 1,7-Bis(4-hydroxyphenyl)-1,4-heptadien-3-one (8) and 5-hydroxy-3,7,3'-trimethoxyflavone-4'-O-beta-D...

extracts derived from viscum album have been shown to kill cancer cells in vitro. some studies have noted that different species of this plant collected from around the world displayed cytotoxic effects in different extents. in the present study, we evaluated the effects of iranian mistletoe extracts on five cancer cell lines. plants growing on hornbeam tree (carpinus betulus) were collected, a...

Background. Breast cancer patients receiving adjuvant chemotherapy often experience a loss of quality of life. Moreover chemotherapy may induce neutropenia. Patients report a better quality of life when additionally treated with mistletoe products during chemotherapy. Methods. In this prospective randomized open-label pilot study 95 patients were randomized into three groups. All patients were ...

In a retrospective study we analysed the survival times of all breast cancer patients treated with mistletoe extract in the Oncology Outpatient Department of the Herdecke Communal Hospital during the period from 1981 to 2000. The survival data for our patients were compared with those for other similar patient populations (tumour registries). The comparatively favourable results from the presen...

BACKGROUND Studies reveal that patients with cancer are actively seeking supportive treatments and may use distinct coping strategies that might be helpful to extend survival time. In this respect, retrolective studies have been applied to examine the therapeutic potential of adjuvant mistletoe treatment. MATERIAL AND METHODS The databases PubMed, EMBASE, AMED, and CAMbase were used to identi...

Additional therapy with extracts of Viscum album [L.] (VaL) increases the quality of life of patients suffering from early stage breast cancer during chemotherapy. In the current study patients received chemotherapy, consisting of six cycles of cyclophosphamide, anthracycline, and 5-Fluoro-Uracil (CAF). Two groups also received one of two VaL extracts differing in their preparation as subcutane...

A retrospective study looked at the survival times of all patients with colorectal cancer who were treated with mistletoe extracts at the Outpatient Oncology Clinic of Herdecke Communal Hospital between 1981 and 2001. The data were compared to corresponding patient data from the Saarland Epidemiological Cancer Registry for the same period. The median survival time of the patients treated with m...