background: hydroxymethylglutaryl‑coenzyme a reductase inhibitors (statins) are antihyperlipidemic drugs with an established efficacy in stabilizing atherosclerotic plaques and preventing atherogenesis and reducing cardiovascular events. the purpose of this study was to determine the effect of simvastatin on serum vitamin d status in dyslipidemic patients as vitamin d status has an impact on mo...

background: it seems that serum vitamin d levels are one of the potential environmental factors affecting the severity of multiple sclerosis (ms). in this study, we aim to evaluate vitamin d levels in ms patients and healthy subjects and assess the relationship between vitamin d level and disability. methods: in this case-control study, 168 rapid relapsing ms patients and 168 matched healthy co...

Vitamin D deficiency is associated with rickets in children, with osteoporosis in the elderly, is thought to increase the risk of certain cancers and of cardiovascular diseases, and may have an impact on many other health conditions. Asians are reported to have a poor vitamin D status despite adequate sunshine in their regions. Data on the extent of vitamin D deficiency at the population level ...

Background: Low vitamin D (vit D) serum levels have been linked to various diseases such as multiple sclerosis, cardiovascular diseases, and diabetes. Maintenance of optimal vit D level should be supported by foods and supplements. Limited food sources of vit D made researchers focus on food fortification in recent years. Methods: A systematic review of randomized controlled trials reporting th...

BACKGROUND The increasingly recognized importance of vitamin D has been discussed and vitamin D status among young children has attracted widespread attention in recent years. However, study on vitamin D status in young children aged 1-3 y is limited in China. OBJECTIVE To evaluate the nutritional vitamin D status of young children aged 1-3 y in Wuxi, southeastern China. METHODS A large coh...

BackgroundVitamin D deficiency is known as a one of the underlying causes of Idiopathic musculoskeletal pain (IMSP). This study aimed to evaluate the correlation between serum vitamin D (Cholecalciferol) status in patient with Non-specific Musculoskeletal Pain and healthy children.Materials and MethodsSeventy-seven children (aged 3–14 years), with IMSP were included as cases and 90 healthy subj...

Vitamin D status of inner-city children aged 1-24 months who reside in İzmir and the factors related with low vitamin D status. 25-hydroxyvitamin D [25(OH)D] is the major circulating form of vitamin D, and its concentrations are the best available indicator of total body vitamin D status. Serum 25(OH)D level depends on factors such as sunlight exposure, seasonal variation, latitude over 40 ̊ nor...

Background and Objectives: Up to date, several pathophysiological mechanisms are suggested for evolution of depression, including inflammation, neurotransmitter and vitamin D pathways. The aim of this study is to evaluate the effects of vitamin D supplementation on serum 25-hydroxycalciferol [25(OH) D], intact parathyroid hormone (iPTH), some pro-inflammatory biomarkers and neurotransmitters su...

since early works on isolation and characterization of vitamin d by elmer verner mccollum and edward mellanby in 1900s, this molecule still seems mysterious (1-2). after several decades since discovery of the miraculous effect of cod liver oil in treatment of nutritional rickets, escalating number of reports provide a huge body of evidence for various effects of vitamin d on human body (3). the...