Neurogenesis occurs throughout adult life in rat dentate gyrus. Factors and mechanisms of adult neurogenesis regulation are not well known. Vitamin E deficiency has been found to deliver a neurogenetic potential in rat dorsal root ganglia. To determine whether the role of tocopherols in adult neurogenesis may be generalized to the central nervous system, changes in adult rat dentate gyrus neuro...

normal 0 false false false en-us x-none ar-sa background: nowadays vitamin d deficiency is a notable medical condition world-wide and also in iran. since, vitamin d can have reoprotective effect by inhibiting the renin-angiotensin system; it appears that low vitamin d level can worsen the renal injury in diabetic patients. this study demonstrates the effect of vitamin d 3 therapy on reducing pr...

vitamin b12 (cobalamin) is an essential coenzyme for nucleic acid synthesis. animal protein is the major dietary source of vitamin b12. deficiency of vitamin b12 leads to megaloblastic anemia, degeneration of the brain, spinal cord, peripheral nerves, and abnormalities of epithelial tissues. two factors are necessary for the cure of megaloblastic anemia: one in food (extrinsic factor) and one i...

background: vitamin d deficiency during pregnancy is associated with some adverse pregnancy outcomes but its relationship with fetal growth is unknown. objective: we compared the 25-hydroxy vitamin d levels between mothers and their small for gestational age (sga) newborns with mothers and their appropriate for gestational age (aga) newborns. materials and methods: the study population included...

BACKGROUND Bariatric surgery has been proven the most effective treatment of morbid obesity, but micronutrient deficiency following bariatric surgery is a major concern. Increasing evidence points to a generally poor micronutrient status in obese subjects. METHODS We assessed micronutrient status in 232 morbidly obese subjects (BMI > or = 35 kg/m(2)) prior to bariatric surgery. Serum albumin,...

Alpha-tocopherol transfer protein (alpha-TTP) is a liver protein responsible for the selective retention of alpha-tocopherol from dietary vitamin E, which is a mixture of alpha, beta, gamma, and delta-tocopherols and the corresponding tocotrienols. The alpha-TTP-mediated transfer of alpha-tocopherol into nascent VLDL is the major determinant of plasma alpha-tocopherol levels in humans. Mutation...

since early works on isolation and characterization of vitamin d by elmer verner mccollum and edward mellanby in 1900s, this molecule still seems mysterious (1-2). after several decades since discovery of the miraculous effect of cod liver oil in treatment of nutritional rickets, escalating number of reports provide a huge body of evidence for various effects of vitamin d on human body (3). the...