Robertson enhances still further their considerable reputation. It shows with disturbing clarity that institutional care facilities just are not geared to meet the emotional needs of small children. A very vulnerable child perhaps we are all becoming immune to the daily diet or horror and misery, the scenes of Biafra, Vietnam and Spanish Harlem on television and in the press. The camera goes on...

Cardiovascular disease is the major cause of morbidity and mortality in subjects suffering from diabetes mellitus. While coronary artery disease is the leading cause of cardiac complications in diabetics, it is widely recognized that diabetes increases the risk for the development of heart failure independently of coronary heart disease and hypertension. This increased susceptibility of the dia...

D uring healthy pregnancy, appropriate levels of fetal nutrition and oxygenation are indispensable for the optimal growth and development of the fetal organs. In pregnancy complicated by decreased nutrient and oxygen delivery to the fetus, current dogma is that the growth and development of key organs, such as the brain, are “spared” at the expense of nonessential organs served by peripheral va...

The recent Enron case has brought to the centre of discussion the question of counterpart risk in derivative transactions, and the issue of correlation between derivative exposure and the main business of the counterpart. Is it wise to buy options on some underlying asset from counterparts that structurally have large exposures to it? A point is that they certainly know the business and the mar...

Plaque Progression: Often Abrupt, Rarely Predictable Some facts are now certain. First, plaque progression and clinical outcome are not always closely related, and each is poorly predicted by clinical and angiographic variables.1–4 Second, many plaques progress episodically because of episodes of thrombosis triggered by rupture, erosion (denudation), or occasionally endothelial activation or in...

Welcome to the first edition of HEX for 2016. We have included some excellent papers, reporting on a range of clinical topics and research methodologies. The review article by Phillipson and colleagues on current practices to increase Chlamydia screening in the community evaluated the included interventions against social marketing national benchmark criteria. Despite the quality of evidence be...