Wear debris in joint replacements has been suggested as a cause of associated tissue-damaging inflammation. In this study, we examined whether solid titanium microparticles (mTi) of sufficient size to accumulate as wear debris could stimulate innate or adaptive immunity in vivo. mTi, administered in conjunction with OVA, promoted total and Ag-specific elevations in serum IgE and IgG1. Analysis ...

A modified impeller mixing coupled with chill casting technique was used for the preparation of immiscible alloys. In this paper Al-Fe binary alloys was chosen for this study. This binary system shows the miscibility gap at specified concentration and temperature. The electrolytic grade iron powder of 300mesh size was dispersed in the melt of commercially pure aluminum. The iron content in the ...

Abstract: Austenitic stainless steels exhibit a low hardness and weak tribological properties. The wear behaviour of austenitic stainless steel AISI 316 was evaluated through the pin on disc tribological method. For investigating the effect of wear on the changes in microstructure and resistance to wear, optical microscopy and scanning electron microscope were used. The hardness of the worn...

The torsional resistance and wear debris generation of the modular sleeve and stem S-ROM total hip system was evaluated. The results indicate that slippage of the sleeve-stem interface may occur under physiological loading conditions. Slippage is more likely to occur if the junction is contaminated by blood or tissue, or if the stem is disengaged and reimplanted into the sleeve. Significant ...

Abstract: Ball mills are used in the last stage of ore processing for grinding raw materials. Forged 70Cr2 alloy steel and Austempered Ductile Iron (ADI) balls are materials from which grinding balls are made for Sarcheshmeh Copper Plant (SCP) ball mills. In the present study wear and impact properties of these two kinds of balls have been investigated. Some balls randomly were selected as ...

INTRODUCTION: Due to increased life expectancy at human population the amount of osteoarthritis of the knee joint will increase. The total knee replacement (TKR) is often the only way to achieve analgesia, to establish the joint function and to correct joint deformation. TKR reached a high grade of quality and safety and has become an often used surgical procedure [1]. TKR most often fail due t...

Wear-debris-induced periprosthetic osteolysis (PIO) is a common clinical condition following total joint arthroplasty, which can cause implant instability and failure. The host response to wear debris promotes bone resorption and impairs bone formation. We previously demonstrated that icariin suppressed wear-debris-induced osteoclastogenesis and attenuated particle-induced osteolysis in vivo. W...

The great success of cemented total hip replacement to treat patients with endstage osteoarthritis and osteonecrosis has been well documented. However, its long-term survivorship has been compromised by progressive development of aseptic loosening, and few hip prostheses could survive beyond 25 years. Aseptic loosening is mainly attributed to bone resorption which is activated by an in-vivo mac...

This paper presents the wear characteristics of the composite ceramic coating made with Al2O3-40wt%8YSZ on the biomedical grade Ti-6Al-4V alloy (grade 5) used for total joint prosthetic components, with the aim of improving their tribological behavior. The coatings were deposited using a plasma spraying technique, and optimization of plasma parameters was performed using response surface method...

Earlier work on the application of the concept of tribopolymerization in reducing wear of ceramics and metals showed striking benefits in both liquid and vapour phase experiments. However, at high rates of frictional heat generation (high load/high speed conditions), several model monomers did not function to reduce wear; in some cases, increases in wear occurred [1]. In recent studies, new cla...