نتایج جستجو برای: wet macular degeneration

تعداد نتایج: 108396  

2017
Christine Wood Pierre Aubert Kurt A. Rosentrater

As studies continue to examine new value added uses for ethanol coproducts, it is important to have means to easily determine the feasibility of the processing steps involved. Many industries widely use computer simulation programs for this purpose, and for planning the use of resources and equipment capacities, and to determine processing costs. The objective of this project was to determine t...

2015
Makoto Ishikawa Daisuke Jin Yu Sawada Sanae Abe Takeshi Yoshitomi

Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly population, and the prevalence of the disease increases exponentially with every decade after the age of 50 years. While VEGF inhibitors are promising drugs for treating patients with ocular neovascularization, there are limitations to their potential for improving vision in AMD patients. Thus, future therap...

Journal: :Science 2006
Andrew Dewan Mugen Liu Stephen Hartman Samuel Shao-Min Zhang David T L Liu Connie Zhao Pancy O S Tam Wai Man Chan Dennis S C Lam Michael Snyder Colin Barnstable Chi Pui Pang Josephine Hoh

Age-related macular degeneration (AMD), the most common cause of irreversible vision loss in individuals aged older than 50 years, is classified as either wet (neovascular) or dry (nonneovascular). Inherited variation in the complement factor H gene is a major risk factor for drusen in dry AMD. Here we report that a single-nucleotide polymorphism in the promoter region of HTRA1, a serine protea...

Journal: :International Journal of Nanomedicine 2006
Stanley A Vinores

Age-related macular degeneration (AMD) is a major cause of severe visual loss worldwide. Neovascular (wet) AMD accounts for 90% of the visual loss associated with the disorder and vascular endothelial growth factor (VEGF) has been shown to play a major role in neovascularization and vascular permeability, the major causes of visual loss in AMD, making it an ideal target for therapeutic interven...

Journal: :PharmacoEconomics 2011
Paul Mitchell Lieven Annemans Richard White Meghan Gallagher Simu Thomas

Age-related macular degeneration (AMD) is a leading cause of blindness in people aged ≥50 years. Wet AMD in particular has a major impact on patient quality of life and imposes substantial burdens on healthcare systems. This systematic review examined the cost-effectiveness data for current therapeutic options for wet AMD. PubMed and EMBASE databases were searched for all articles reporting ori...

2015
James E Neffendorf Timothy L Jackson

Neovascular age-related macular degeneration is a leading cause of blindness in the developed world. Currently, the treatment of choice is intravitreal injections of anti-VEGF medications. These require frequent dosing, up to monthly, and impose a substantial burden on patients and the health economy. Ionizing radiation was proposed as a possible treatment for age-related macular degeneration d...

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