We present a population density and moment-based description of the stochastic dynamics of domain Ca-mediated inactivation of L-type Ca channels. Our approach accounts for the effect of heterogeneity of local Ca signals on whole cell Ca currents; however, in contrast with prior work, e.g., Sherman et al. (1990), we do not assume that Ca domain formation and collapse are fast compared to channel...

|Evolutionary artiicial neural networks (EANNs) refer to a special class of artiicial neural networks (ANNs) in which evolution is another fundamental form of adaptation in addition to learning. Evolution can be introduced at various levels of ANNs. It can be used to evolve weights, architectures, and learning parameters and rules. This paper is concerned with the evolution of ANN architectures...

Statistical inference is commonly said to be inapplicable to complete population studies, such as censuses, due to the absence of sampling variability. Nevertheless, in recent years, studies of whole populations, e.g., all cases of a certain cancer in a given country, have become more common, and often report p values and confidence intervals regardless of such concerns. With reference to the s...