Significant inhibition of lymphoid tumor development was observed in X-irradiated strain C57BL mice treated with multiple injections of rat antiserum prepared by im munization of Wistar-Furth or (Wistar-Furth-BN) F, rats with histocompatible lymphomas induced by the radiation leukemia virus (RadLV). However, there was also signifi cant inhibition, relative to phosphate-buffered saline con trols...

Significant inhibition of lymphoid tumor development was observed in X-irradiated strain C57BL mice treated with multiple injections of rat antiserum prepared by im munization of Wistar-Furth or (Wistar-Furth-BN) F, rats with histocompatible lymphomas induced by the radiation leukemia virus (RadLV). However, there was also signifi cant inhibition, relative to phosphate-buffered saline con trols...

The spontaneously hypertensive rat and the Dahl salt-sensitive rat are the most widely studied genetic models of hypertension. Many investigators have attempted to study the pathogenesis of hypertension by comparing these strains with their respective normotensive "controls," the Wistar-Kyoto rat and the Dahl salt-resistant rat. However, the genetic relation between each of these hypertensive s...

Atherosclerosis is arterial wall’s disease initiated by lipid retention, oxidation, and modification, provoking chronic inflmmation ultimately causing stenosis thrombosis. This study investigated the effect of alpha lipoic acid (ALA) on thoracic aorta type 2 diabetic rat. Fifteen adult male rat Rattus novergicus Wistar strain were separated into three groups (n=5), there labelled as control, di...

Time-related changes in the incidences of spontaneous neoplasms in skin (fibroma and keratoacanthoma), thyroid (C-cell and follicular cell adenomas/carcinomas), uterus (stromal polyp), testes (Leydig cell tumor) and hemolymphoreticular system (mesenteric lymph node hemangioma and malignant granular lymphocytic leukemia) were assessed statistically in Wistar, Sprague-Dawley and F344 rats employe...

BACKGROUND: Coffee arabica gayo leaf extract (Coffea L.) contains polyphenols (chlorogenic acid), flavonoids, saponins, tannins, and steroids which improved PI3K serum levels in rats type 2 diabetic rat. AIM: The purpose of the study was to determine effect Arabica Gayo Leaf Extract (C. on increased type-2 rat (Rattus norvegicus). METHODS: Thirty-five male Wistar with induced a combination feed...

BioBreeding (BB) rats are derived from an outbred colony of Wistar rats and are used as a model of autoimmune diabetes mellitus. A corticosteroid binding globulin (CBG) variant with reduced affinity for glucocorticoids has now been found in the blood of these animals. The dissociation rate constants of BB CBG for cortisol (4.42 nM) and corticosterone (1.43 nM) are both about 50% higher than tho...