The study of wound closure is important for the advancement of medicinal applications in surgical scar healing, as well as initiation of tissue regeneration. Research on wound closure has primarily focused on vertebrate models, although the process is found throughout all animal groups. Non-vertebrate models provide efficient cost-effective tools for examining the general properties necessary f...

OBJECTIVE To compare the clinical outcomes of staples versus sutures in wound closure after orthopaedic surgery. DESIGN Meta-analysis. DATA SOURCES Medline, CINAHL, AMED, Embase, Scopus, and the Cochrane Library databases were searched, in addition to the grey literature, in all languages from 1950 to September 2009. Additional studies were identified from cited references. Selection criter...

BACKGROUND Fasciotomy incisions for limb compartment syndrome usually cannot be closed primarily. The conventional method of wound closure with split-thickness skin grafting is effective, but it results in an insensate and disfiguring wound and is associated with donor site morbidity. We present our experience in delayed primary closure of fasciotomy wounds with Wisebands (WB), a skin- and soft...

BACKGROUND/PURPOSE Wound management in children has traditionally consisted of daily dressings. Although vacuum-assisted closure (VAC) is well described in the adult literature, there are few reports about children. We reviewed our experience with VAC. METHODS A retrospective review from 2003 to 2005 revealed that 16 children underwent VAC. Variables analyzed included demographics, diagnosis,...

The study of wound closure is important for the advancement of medicinal applications in surgical scar healing, as well as initiation of tissue regeneration. Research on wound closure has primarily focused on vertebrate models, although the process is found throughout all animal groups. Non-vertebrate models provide efficient cost-effective tools for examining the general properties necessary f...

UNLABELLED Resection of musculoskeletal tumors may result in large soft tissue defects that cannot be closed primarily and require prolonged dressing changes and complex surgical interventions for wound coverage. We retrospectively reviewed 23 patients with such defects treated with a vacuum-assisted wound closure system and compared the outcome of these patients with a control group. The study...

BACKGROUND It is still a matter of debate whether delayed primary closure (DPC) of contaminated abdominal incisions reduces surgical site infections compared with a primary closure (PC). The aim of this study was to determine the optimal method of wound closure for patients with perforated appendicitis. METHODS A total of 70 patients with perforated appendicitis were included. They were rando...

Stress-relaxation is a well-established mechanism for laboratory skin stretching, with limited clinical application in conventional suturing techniques due to the inherent, concomitant induction of ischemia, necrosis and subsequent suture failure. Skin defects that cannot be primarily closed are a common difficulty during reconstructive surgery. The TopClosure tension-relief system (TRS) is a n...