gum tragacanth is a natural complex mixture of polysaccharides and alkaline minerals extracted from species of astragalus plant, which is found widely in arid regions of the middle east. in a pilot experimental study we examined the effects of its topical application on wound healing in ten albino adult male rats. two similar parasagittal elliptical full-thickness wounds (control vs. test sampl...

conclusions the results showed the effectiveness of bromelain on episiotomy pain and wound healing. therefore, it is suggested to use bromelain in postoperative stage to improve wound healing and reduce pain. background ananas comosus has long been used for medical purposes. currently, we are experiencing an unprecedented interest in the use of complementary medicine as well as a growing attent...

objective: to determine the effects of topical administration of 20% oltipraz solution on histomorphometrical and stereological aspects of skin tissue in full thickness skin wounds in laboratory rats. methods: thirty-six male wistar portion rats (220±20 g) were randomly divided into three groups (n=12). on the first day of experimentation, a 1-cm 2 circular wound was made on the posterior surfa...

Nanofiber meshes holds great promise in wound healing applications by mimicking the topography of extracellular matrix, hence providing guidance for crucial cells involved in the regenerative processes. Here we explored the influence of nanofiber alignment on fibroblast behavior in a novel in vitro wound model. The model included electrospun poly-ε-caprolactone scaffolds with different nanofibe...

The ethyl acetate fraction from ethanolic extract of Wedelia trilobata (L.) leaves displayed wound healing properties. The ethyl acetate fraction was further subjected to bioassay-guided fractionation which afforded isolation of grandiflorenic acid which requires further investigation to prove its wound healing potential. The grandiflorenic acid from leaves of Wedelia trilobata was assessed for...

Urethral healing is plagued by strictures, impacting quality of life and medical costs. Various growth factors (GFs) have shown promise as therapeutic approaches to improve healing, but there no protocol for in vitro comparison between GFs. This study focuses the development a biomimetic urothelial assay designed mimic early vivo followed an evaluation cell response Methods: Wound-healing assay...

Objective: To investigate the in vitro antioxidant, antimicrobial, anticancer, and wound healing properties of leaf extracts Acanthus ilicifolius.
 Methods: ilicifolius leaves were dried prepared using different solvents cold extraction method. The preliminary phytochemical analysis quantitative methods carried out standard procedures. In antioxidant activity was evaluated DPPH assay. Disc...

OBJECTIVE To observe the promoting effect of arnebia root oils on expression of basic fibroblast growth factor (bFGF) in skin wound of rabbits and the histomorphological changes in the wound surface, and to discuss its mechanism. METHODS Bilateral round skin wounds were made on the back of 15 rabbits. The three wounds on one side of the back of each rabbit were treated with arnebia root oils,...

Wound healing is a complex series of biochemical and cellular events. Optimally, functional material design addresses the overlapping acute and inflammatory stages of wound healing based on molecular, cellular, and bio-compatibility issues. In this paper the issues addressed are uncontrolled hemostasis and inflammation which can interfere with the orderly flow of wound healing. In this regard, ...

Objective(s): Lapachone is a natural naphthoquinone-derived compound found in Tabebuia avellanedae. It is well-known for its analgesic, anti-inflammatory, anti-microbial, diuretic, and anti-cancerous effects. However, the wound-healing effects of this compound are not known yet. The aim of this study was to investigate the wound healing activity of naphthoquinones (α-l...