objective: dendrimers are three-dimensional nanostructures that have numerous applications in medicine, including drug delivery and imaging. although anionic dendrimer polyethylene glycol–citrate has a high potential to increase solubility of water-insoluble drugs and drug delivery, its multi-step synthesis procedure is time consuming. in addition, toxic substances such as dichloromethane are u...

The paper presents a concept of support for the design and analysis of Internet security systems with a rule-based methodology. It considers a web security architecture, including a network and applicationlevel firewall with intrusion detection systems. The XTT methodology allows for hierarchical design, and on-line analysis of rule-based systems. It is applied using the Unified Firewall Model,...

The paper deals with some common problems present in knowledge and software engineering, related to the practical design, analysis, and implementation of systems. With different design methods used at subsequent design stages, the socalled semantic gaps appear, due to important differences in semantics between design methods. The paper discusses the semantic gaps present in software and knowled...

Fungal infections and antifungal resistance are increasingly recognized. Antifungal susceptibility testing remains unstandardized, and a particularly important problem is endpoint determination. In this paper we propose the yeast metabolic reduction of the tetrazolium salt 2,3-bis(2- methoxy-4-nitro-5-sulfophenyl)-5-[(phenylamino)carbonyl]-2H-tetraz olium hydroxide (XTT) as a colorimetric endpo...