Remarkable progress has been achieved in understanding the mechanisms controlling sex determination, yet the cause for many Disorders of Sex Development (DSD) remains unknown. Of particular interest is a rare XX DSD subtype in which individuals are negative for SRY, the testis determining factor on the Y chromosome, yet develop testes or ovotestes, and both of these phenotypes occur in the same...

Background: Mosaicism of a normal cell population and an unbalanced autosomal chromosome rearrangement is rarely seen. If the abnormal cell line contributes to a minor part of soma, the phenotype is expected to be normal. Case Report: We report a 29-year-old woman who had balance chromosomal translocation of 46,XX,t(5;21) with a 2-year-old affected girl, characterized by mental retardation, dys...

http://bioscience.oxfordjournals.org XXXX XXXX / Vol. XX No. X • BioScience 1 BioScience XX: 1–12. © The Author(s) 2014. Published by Oxford University Press on behalf of the American Institute of Biological Sciences. All rights reserved. For Permissions, please e-mail: [email protected]. doi:10.1093/biosci/bit017 Advance Access publication XXXX XX, XXXX Reconstructing Disturbances a...

www.bioscience.oxfordjournals.org XXXX XXXX / Vol. XX No. X • BioScience 1 BioScience XX: 1–9. © The Author(s) 2013. Published by Oxford University Press on behalf of the American Institute of Biological Sciences. All rights reserved. For Permissions, please e-mail: [email protected]. doi:10.1093/biosci/bit003 Advance Access publication XXXX XX, XXXX Linking Biodiversity and Ecosyste...

Each Carnegie Mellon course number begins with a two-digit prefix which designates the department offering the course (76-xxx courses are offered by the Department of English, etc.). Although each department maintains its own course numbering practices, typically the first digit after the prefix indicates the class level: xx-1xx courses are freshmen-level, xx-2xx courses are sophomore level, et...

Each Carnegie Mellon course number begins with a two-digit prefix which designates the department offering the course (76-xxx courses are offered by the Department of English, etc.). Although each department maintains its own course numbering practices, typically the first digit after the prefix indicates the class level: xx-1xx courses are freshmen-level, xx-2xx courses are sophomore level, et...

Each Carnegie Mellon course number begins with a two-digit prefix which designates the department offering the course (76-xxx courses are offered by the Department of English, etc.). Although each department maintains its own course numbering practices, typically the first digit after the prefix indicates the class level: xx-1xx courses are freshmen-level, xx-2xx courses are sophomore level, et...

http://bioscience.oxfordjournals.org XXXX XXXX / Vol. XX No. X • BioScience 1 BioScience XX: 1–11. © The Author(s) 2014. Published by Oxford University Press on behalf of the American Institute of Biological Sciences. All rights reserved. For Permissions, please e-mail: [email protected]. doi:10.1093/biosci/biu045 Advance Access publication XXXX XX, XXXX Experimental Evolution of Mul...

In this article, we have obtained some novel results on bilateral generating functions of the polynomials, YYnn+rr αα−nnnn(xx;kk), a modified form of Konhauser biorthogonal polynomials, YYnn(xx; kk) by group-theoretic method. As special cases, we obtain the corresponding results on Laguerre polynomials, LLnn αα(xx). Some applications of our results are also discussed.