The purpose of this study is to evaluate the suitability of five different anesthetic protocols (isoflurane, isoflurane–xylazine, pentobarbital, ketamine–xylazine, and ketamine–xylazine–vecuronium) for functional blood flow imaging in the rat eye. Total retinal blood flow was measured at a series of time points using an ultrahigh-speed Doppler OCT system. Additionally, each anesthetic protocol ...

Introduction: This experimental study was designed to study the effects of ascorbic acid (vitamin C = VitC) for premedication on ketamine/xylazine anaesthesia in the rat. Material and methods: Fifty albino laboratory rats (Sprague-Dawley) of either sex were divided into five groups (A, B, C, D and E) of ten rats in each. Rats in groups C, D and E were pre-treated with 50, 100 and 150 mg/kg, res...

Aim: The study was undertaken to compare the clinical efficacy of lumbosacral spinal analgesia produced using bupivacaine, xylazine and buprenorphine with ketamine combination in buffalo calves Materials and Methods: 36 male buffalo calves of seven to eight months of age and weighing 60 to 75 kg were used to evaluate the efficacy and safety of lumbosacral spinal analgesia produced by bupivacain...

JANICKI, Z., D. KONJEVIĆ, A. SLAVICA, K. SEVERIN: Reversible chemical immobilization of wild red deer (Cervus elaphus L.) using tiletamine-zolazepam xylazine hydrochloride mixture. Vet. arhiv 76, 237-244, 2006. ABSTRACT Fifteen live-trapped red deer (Cervus elaphus L.) were immobilized during January 2002 in the Baranja region of Croatia. The main purpose of the manipulation was the first indiv...

Endogenous opioids have been implicated in compound-induced antinociception, and our group previously suggested that xylazine induces peripheral antinociception by releasing endogenous opioids that act on their respective receptors. In this study, we investigated the involvement of endogenous opioids in α2-adrenoceptor agonist xylazine-induced central antinociception. The nociceptive threshold ...

AIM To test if anesthetic procedures change the hemodynamic pattern in animals with experimental septic shock. METHODS The effect of two anesthetics on systemic hemodynamic and skeletal muscle microcirculatory responses in high cardiac output live E. coli bacteremia was studied in rats and compared to the effect of two other anesthetic procedures in previously published studies. RESULTS Bas...

Yohimbine, 4-aminopyridine, and a combination of the 2 drugs were studied to assess their potential as antagonists to xylazine in goats. Twenty-four small East African goats were divided randomly into 4 groups of 6 goats each in a placebo-controlled study. They were all treated with intramuscular xylazine at 0.44 mg/kg. At the time of maximum sedation, sterile water was administered intravenous...

ABSTRACT Introduction: Oral mucositis (OM) is considered the most frequent acute side effect of antineoplasic treatment, with ulcerative lesions resulting from a painful symptomatology, affecting oral cavity in response to Antineoplastic treatment. In order study these effects, experiments animal models are necessary, using antineoplastic drugs for induction OM and anesthetics, mainly Ketamine ...

1. The effect of yohimbine (Y) on blood levels of thyroxine (T4), triiodothyronine (T3), and cortisol was investigated in 5 mature male white-tailed deer immobilized with xylazine hydrochloride (X). 2. T4 levels were erratic in X-treated deer, but stabilized in the X- and Y-treated deer. 3. T3 remained unchanged in both groups. 4. Cortisol levels have increased in X-treated deer, but declined i...

BACKGROUND The effect of intranasal oxygen and/or early reversal of xylazine with atipamezole on arterial oxygenation in free-ranging moose (Alces alces) immobilized with etorphine-acepromazine-xylazine with a cross-sectional clinical study on 33 adult moose was evaluated. RESULTS Before treatment the mean±SD (range) partial pressure of arterial oxygen (PaO2) was 62±17 (26-99) mmHg. Twenty-si...