BACKGROUND Due to the rarity of testicular tumors in the prepubertal population, adequate information about their biological course is difficult to document well in a single institution. The purpose of this study was to focus on prepubertal males in an attempt to evaluate clinical features and optimal management among various testicular germ cell tumors with long-term follow-up. METHODS We re...

The sex-linked gene for imperfect albinism (S*ALS) has been associated with slow early growth in some trials but not in others. Albino (59) and nonalbino (73) chicks were raised to 3 d of age to study early growth. At 3 d of age, plasma beta-hydroxybutyrate (beta-HBA) levels were measured and the chicks were euthanatized and dissected to measure liver, gall bladder, and yolk sac weights. Fatty ...

Conceptuses from 9-5-day pregnant rats have been cultured for 48 h in heat-inactivated homologous serum. Embryonic development was normal. The protein contents of embryos and visceral yolk sacs after different periods of culture were recorded. When I-labelled polyvinylpyrrolidone or [H]dextran were added to the culture serum, radioactivity was accumulated by the yolk sac, but only background le...

Reproductive technologies are widely used in cattle, although many are associated with high-embryonic mortality, especially during early gestation, when the yolk sac undergoes macroscopic changes in structure. We hypothesized that vasculogenesis and angiogenesis are affected, thereby affecting embryonic and placental differentiation. To test this, we studied yolk sac development and gene expres...

Using spectrofluorimetry and fluorescence microscopy, we analyzed the uptake and degradation of fluorescein isothiocyanate-conjugated bovine serum albumin (FITC-albumin) by the rat visceral yolk sac (VYS) during whole embryo culture. Rat conceptuses exposed continuously to FITC-albumin had linear increases of both acid-soluble and acid-insoluble FITC fluorescence in the VYS. Smaller amounts of ...

The uptake of [3H]leucine by the rat yolk sac and embryo and the subsequent synthesis of albumin and transferrin have been studied in whole embryo culture. Rat embryos of 12 days gestation were used in all experiments. Isotopically labelled transferrin was detectable in yolk-sac and embryo tissue extracts. In contrast, [3H]albumin could not be found in either tissue extract. Levels of radioacti...

The yolk sac is phylogenetically the oldest of the extraembryonic membranes. The human embryo retains a yolk sac, which goes through primary and secondary phases of development, but its importance is controversial. Although it is known to synthesize proteins, its transport functions are widely considered vestigial. Here, we report RNA-sequencing (RNA-seq) data for the human and murine yolk sacs...