Ziziphus mauritiana (Lamk.) is a fruit tree that has folkloric implications against many ailments and diseases. In the present study, anticancer potential of seed extract of Ziziphus mauritiana in vitro against different cell lines (HL-60, Molt-4, HeLa, and normal cell line HGF) by MTT assay as well as in vivo against Ehrich ascites carcinoma bearing Swiss albino mice was investigated. The extr...

The in vitro antibacterial activities of 29 traditional medicinal plants used in respiratory ailments were assessed on multidrug resistant Gram-positive and Gram-negative bacteria isolated from the sore throat patients and two reference strains. The methanolic, n-hexane, and aqueous extracts were screened by the agar well diffusion assay. Bioactive fractions of effective extracts were identifie...

Günümüzde sağlık alanında birçok konuda modern tıp pratiğine yardımcı olarak faydalanılabilen geleneksel ve tamamlayıcı uygulamalarına olan ilgi her geçen gün artmaktadır. Hünnap (Ziziphus jujuba Mill.) bitkisi de bu bağlamda uzun süredir araştırmacıların odağında yer almaktadır. Yapılan çalışmalarda başlıca antienflamatuar, antihiperglisemik, antihiperlipidemik, antimikrobiyal özellikleri olan...

objective(s):the neuroprotective effect offruit aqueous extract of ziziphus jujuba lam on glucose-induced neurotoxicity in pc12 cells as an appropriate in vitro model of diabetic neuropathy was investigated. materials and methods: cell viability was determined by the mtt assay. cellular reactive oxygen species (ros) generation was measured by dcfh-da analysis. cleaved caspase-3, a biochemical p...

Ziziphus mauritiana L., is a fruit tree well known for its nutritional and medicinal benefits. The aim of the current study was to investigate the chemical composition as well as biological (antioxidant, antimicrobial, antitumor and anticancer) attributes of different solvent extracts from the leaves of Ziziphus mauritiana. It was established by colorimetric method that chloroform extract had g...

Chronic alcohol ingestion is known to increase the generation of reactive oxygen species (ROS), thereby leading to liver damage. Antioxidant enzymes act individually or in combination to reduce or counter the effect of these ROS. Chronic administration of alcohol at (40% v/v, 1 ml/100 g), for 6 weeks showed a significant (p<0.05) elevated levels of alanine aminotransferase (ALT), aspartate amin...

Jujube (Ziziphus jujuba Mill.) belongs to the Rhamnaceae family and is a popular fruit tree species with immense economic and nutritional value. Here, we report a draft genome of the dry jujube cultivar 'Junzao' and the genome resequencing of 31 geographically diverse accessions of cultivated and wild jujubes (Ziziphus jujuba var. spinosa). Comparative analysis revealed that the genome of 'Dong...

BACKGROUND Pediatric infectious disease is one of the main problems in cancerous children that treat by chemotherapy drugs. Thus, study in this regard is necessary. The aim of this study was to evaluate antimicrobial properties of ethanolic extract of Ziziphus Jujuba fruits against different infectious pathogens. MATERIALS AND METHODS This study is descriptive. In vitro antimicrobial activity...

Background: Tonsillitis is an inflammation of the palatine tonsil that often found in otorhinolaryngology and one world's socio-economic health problems. Streptococcus pyogenes most common bacterial cause tonsillitis, with hydrophobicity phospholipase activity on cell surface has a major effect tonsillitis pathogenicity. Ethanol extract leaves sea bidara (Ziziphus mauritiana) antibacterial impa...