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Dear Sir: In a recent article, Edupuganti and others reported a clinical study of co-administration of subcutaneous yellow fever (YF) 17D vaccine (YF-VAX Ò ; Sanofi Pasteur, Lyon, France) and intramuscular immune serum globulin (ISG) (amaSTAN S/D Ò ; Talecris Biotherapeutics, Research Triangle Park, NC) or saline placebo. 1 The study was designed to test whether co-administration of vaccine and...

Which kind of intellectual property regime is more favorable to innovation: one that enforces patents or one that does not? Economic theory is unable to answer this question, as valid arguments can be made both for and against patents; hence we must turn to empirical evidence. In this paper, we review empirical evidence gathered by other researchers and add new evidence of our own. We conclude ...

An algorithm for the computation of the stochastic non-stationary non-linear response of large FE-models is presented. In stochastic analysis, the response is described by the mean and covariance function and possibly by the probability distribution of the non-linear response. To estimate the covariance matrix, the method of Equivalent Statistical Linearization (EQL) is applied for linearizing ...