To examine the concordance of two metabolizing systems for use in genotoxocity testing with the micronucleus test, 15 naturally occurring substances (arecoline, the plant extract aristolochic acid, beta-asarone, benzyl acetate, coumarin, emodine, isatidine dihydrate, monocrotaline, psoralen, reserpine, retrorsine, safrole, sanguinarine chloride, tannin and thiourea) were tested for their genoto...

BACKGROUND Acori Tatarinowii Rhizoma (ATR; rhizome of Acorus tatarinowii Schott) (Shi Chang Pu) is widely used in Chinese medicine (CM) to resuscitate, calm the mind, resolve shi (dampness) and harmonize the wei (stomach). Seven different species have been identified as belonging to the genus Acorus, all of which can be found in China. However, it can be difficult to distinguish the different s...

We investigated the anxiolytic-like activity of α-asarone (AAS) from Acorus gramineus in an experimental rat model of anxiety induced by repeated administration of the exogenous stress hormone corticosterone (CORT). The putative anxiolytic effect of AAS was studied in behavioral tests of anxiety, such as the elevated plus maze (EPM) test and the hole-board test (HBT) in rats. For 21 consecutive...

Objectives: Anti ischemic reperfusion effect of crude methanol extract of Desmodium gangeticum root had been reported earlier but how is modulating its cardiotonic effect to render cardio-protection is largely unknown. Methods: The inotropic effect of methanol extract of Desmodium gangeticum root was investigated on isolated frog heart and further analyzed the physiological and biochemical effe...

Secondary metabolites are chemical found in plants. These have no role in plant growth but these are important for human because it have many pharmacological activity. Bergenia species such as Bergenia stracheyi, Bergenia ligulata And Bergenia ligulata etc. have many secondary metabolites such as 1. Bergenin 2. Tannic acid 3. Gallic acid 4. Stigmesterol 5. β-Sitosterol 6. catechin 7. (+)-Afzele...