Interferons (IFNs) are secreted cytokines with the ability to activate expression of IFN stimulated genes that increase resistance cells virus infections. Activated transcription factors in conjunction chromatin remodelers induce epigenetic changes reprogram responses. Unexpectedly, 8-oxoguanine DNA glycosylase1 (Ogg1) knockout mice show enhanced stimuli-driven confers increased viral and bacte...