Antrodia camphorata grown on germinated brown rice (CBR) was prepared to suppress melanoma development. CBR extracts were divided into hexane, EtOAc, BuOH, and water fractions. Among all the fractions, EtOAc fraction showed the best suppressive effect on B16F10 melanoma cell proliferation by CCK-8 assay. It also showed the increased cell death and the changed cellular morphology after CBR treat...

One advantage of Case-Based Reasoning (CBR) is the relative ease of constructing and maintaining CBR systems, especially as a number of commercial CBR tools are available. However, there are areas of CBR that current tools have not yet addressed. One of these is easing or automating the acquisition of adaptation knowledge. Since tasks like design or planning typically require a significant amou...

This paper looks at EBMT from the perspective of the Case-based Reasoning (CBR) paradigm. We attempt to describe the task of machine translation (MT) seen as a potential application of CBR, and attempt to describe MT in standard CBR terms. The aim is to see if other applications of CBR can suggest better ways to approach EBMT.

Case-Based Reasoning (CBR) means reasoning from experiences (old cases) in an effort to solve problems, critique solutions and explain anomalous situations. The CBR approach to problem-solving and learning has got a lot of attention within the Artificial Intelligence’s community over the last few years, because as an intelligent-systems’ method enables information managers to increase efficienc...

The particular strength of CBR is normally considered to be its use in weak theory domains where solution quality is compiled into cases and is reusable. In this paper we explore an alternative use of CBR in optimisation problems where cases represent highly optimised structures in a huge highly constrained solution space. Our analysis focuses on the Travelling Salesman Problem where difficulty...

OBJECTIVE Medical applications have special features (interpretation of results in medical metrics, experiment reproducibility and dealing with complex data) that require the development of particular tools. The eXiT*CBR framework is proposed to support the development of and experimentation with new case-based reasoning (CBR) systems for medical diagnosis. METHOD Our framework offers a modul...

OBJECTIVES Clinical benefit response (CBR), based on changes in pain, Karnofsky performance status, and weight, is an established palliative endpoint in trials for advanced gastrointestinal cancer. We investigated whether CBR is associated with survival, and whether CBR reflects a wide-enough range of domains to adequately capture patients' perception. METHODS CBR was prospectively evaluated ...