APS [for 'adapter protein with a pleckstrin homology (PH) and Src homology 2 (SH2) domain'] belongs to a family of adapter proteins involved in signalling by the receptors for insulin, insulin-like growth factor 1, platelet-derived growth factor and nerve growth factor. Other members include alternatively spliced SH2-B isoforms (SH2Balpha, SH2-Bbeta and SH2-Bgamma) and Lnk. These have a C-termi...

Play is a natural mode of children's expression and constitutes a fundamental aspect of their life. Cognitive, affective, and social aspects can be assessed through play, considered as a "window" to observe a child's functioning. According to Russ's model, cognitive and affective components and their reciprocal connections can be assessed through the Affect in Play Scale (APS). The aim of the p...

BACKGROUND Heart valves lesions and central nervous system involvement are among the most common manifestations of the antiphospholipid syndrome (APS). OBJECTIVE To evaluate possible interrelations between these manifestations in a large group of APS patients. METHODS 284 APS patients were evaluated retrospectively, 159 of whom had primary APS. Cardiac-CNS associations were determined for t...

In recent years, the molecular and genomic revolutions have overshadowed the more traditional discipline of physiology and its focus on functions within living organisms. As the scientific world has been deluged with information, the importance of interpreting this information in a functional context has been rediscovered, and physiology has been reinvented, albeit with new names such as functi...

BACKGROUND There has been debate on which blood components should be included in autologous therapies. Autologous Protein Solution (APS) is a unique blood-derived therapy composed of concentrated white blood cells, platelets, and plasma to contain high concentrations of anti-inflammatory cytokines and anabolic growth factors to potentially address osteoarthritis. The primary aim of the explorat...

Advanced vehicle content distribution system (ACDS)is complemented by improved network connectivity with Mobile Network 3G, 4G network. Advanced content distribution system uses Access Points deployed along roadside. APs coordinate and collaborate to distribute content to vehicles in mobility. The infrastructure of deployed APs solves real time issues like predicting errors in movement, limited...

Background: Heart valves lesions and central nervous system involvement are among the most common manifestations of the antiphospholipid syndrome (APS). Objective: To evaluate possible interrelations between these manifestations in a large group of APS patients. Methods: 284 APS patients were evaluated retrospectively, 159 of whom had primary APS. Cardiac–CNS associations were determined for th...

This paper is motivated by a recent result of Wolf [12] on the minimum number of monochromatic 4-term arithmetic progressions (4-APs, for short) in Zp, where p is a prime number. Wolf proved that there is a 2-coloring of Zp with 0.000386% fewer monochromatic 4-APs than random 2-colorings; the proof is probabilistic and non-constructive. In this paper, we present an explicit and simple construct...

Previous studies have shown that Astragalus polysaccharides (APS) can be used to treat general gastrointestinal disturbances including intestinal mucosal injury. However, the mechanism by which APS mediate this effect is unclear. In the present study, the effects of APS on proliferation, migration, and differentiation of intestinal epithelial cells (IEC-6) were assessed using an in vitro woundi...

The antiphospolipid syndrome (APS) is an autoimmune disease characterized by recurrent fetal loss, thrombotic events (arterial or venous) and hemocytopenic disorders associated to high titers of circulating aPL. Two variants of the APS have been described. Primary APS is a clinical entity without evidence of any other autoimmune disease and secondary APS is a clinical disorder mainly associated...