BACKGROUND Kearns-Sayre Syndrome (KSS) is a multisystem disorder caused by a dysfunction of the oxidative phosphorylation system within mitochondria. Mitochondrial DNA (mtDNA) rearrangements are a key molecular feature of this disease, which manifest a broad phenotypic spectrum. CASE PRESENTATION Here, we present a boy with KSS whose symptoms included cardiac conduction deficit, cardiomyopath...

This paper describes the development of explicit time-stepping methods for linear partial differential equations that are specifically designed to cope with the stiffness of the system of ordinary differential equations that results from spatial discretization. As stiffness is caused by the contrasting behavior of coupled components of the solution, it is proposed to adopt a componentwise appro...

The numerical solution of a time-dependent PDE generally involves the solution of a stiff system of ODEs arising from spatial discretization of the PDE. There are many methods in the literature for solving such systems, such as exponential propagation iterative (EPI) methods, that rely on Krylov projection to compute matrix function-vector products. Unfortunately, as spatial resolution increase...

We investigated the long-term changes in the Harris Hip and Knee Society scores (HSS and KSS) to determine whether they result from overall functional decline rather than actual changes in the condition of the prosthesis. The HHS for 106 total hip arthroplasties with a minimum follow-up of ten years, no medical complications after operation and no evidence of radiological loosening, and the KSS...

To cite: Sharma AK, Jain N, Kharwar RB, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2016216500 DESCRIPTION We describe the images of a 27-year-old man presenting with recurrent syncope due to complete heart block (figure 1). The patient, on further examination, showed ophthalmoplegia, bilateral ptosis (figure 2) and pigmentary retinopathy (figure 3). Ke...

This paper examines the sustainability of current account in 27 European Union countries over period 2005Q1-2020Q3. First, series which is considered as ratio to gross domestic product, was applied traditional unit root test ADF and nonlinear KSS. According test, stationary 9 according KSS 5 countries. Later, FADF FKSS tests based on Fourier were applied. results, found 10 for 3 FKSS. results a...

Kearns-Sayre syndrome (KSS) is a rare mitochondrial disorder, and the effects of radiotherapy on such population group are unknown. A 60-year-old male with history KSS was diagnosed locally advanced basal cell carcinoma along left inner canthus. He treated at our institution curative intent alone tolerated it well no major acute or late toxicities. There complete clinical radiological response ...

background: we determined the levels of subjective and observer drowsiness and facial dynamics changes. methods: this experimental study was done in the virtual reality laboratory of khaje-nasir toosi university of technology in 2015. facial dynamics changes like changes in eyes, mouth and eyebrows were surveyed on twenty-five drivers in 2015bykss (karolinska sleepiness scale) and ord (observer...

Comparing different novel feature sets and classifiers for speech processing based fatigue detection is the primary aim of this study. Thus, we conducted a within-subject partial sleep deprivation design (20.00–04.00 h, N1⁄477 participants) and recorded 372 speech samples of sustained vowel phonation. The self-report on the Karolinska Sleepiness Scale (KSS) and an observer report on the KSS, th...