نتایج جستجو برای: اصل 139

تعداد نتایج: 27989  

Journal: :Journal of Applied Polymer Science 2021

In the article from Shuling Zhang and Youmei Ma, Silica nanoparticles with a refractive index matching poly (propylene carbonate) (PPC) diameter smaller than visible light wavelength were chosen to prepare transparent PPC/silica nanocomposites enhanced properties using simple melt compounding method. Details can be found in their article. DOI: 10.1002/app.51513

Journal: :Journal of immunology 2008
Keith W Wegmann Cynthia R Wagner Ruth H Whitham David J Hinrichs

Multiple Ag peptides (MAPs) containing eight proteolipid protein (PLP)(139-151) peptides arranged around a dendrimeric branched lysine core were used to influence the expression and development of relapsing experimental allergic encephalomyelitis (EAE) in SJL mice. The PLP(139-151) MAPs were very efficient agents in preventing the development of clinical disease when administered after immuniza...

2016
Ke Xu Ke Shen Xin Liang Yueqi Li Norio Nagao Jiyu Li Jianwen Liu Peihao Yin

MiRNAs may promote or inhibit tumor recurrence and drug resistance. MiR-139-5p is reportedly downregulated in colorectal cancer patient samples, but it is unknown whether and how miR-139-5p regulates drug resistance. Cancer stem cells (CSCs) are postulated to be important promoters of multiple drug resistance (MDR). In this study, we established a MDR cell model which strongly expressed the CSC...

2015
Kousuke Watanabe Yosuke Amano Rie Ishikawa Mitsuhiro Sunohara Hidenori Kage Junji Ichinose Atsushi Sano Jun Nakajima Masashi Fukayama Yutaka Yatomi Takahide Nagase Nobuya Ohishi Daiya Takai

MicroRNA expression is frequently altered in human cancers, and some microRNAs act as oncogenes or tumor suppressors. MiR-139-5p (denoted thereafter as miR-139) has recently been reported to function as a tumor suppressor in several types of human cancer (hepatocellular carcinoma, colorectal cancer, breast cancer, and gastric cancer), but its function in non-small-cell lung cancer (NSCLC) and t...

2017
Yingjun Cui Xia Sun Lianfeng Jin Guangpu Yu Qingzhang Li Xuejun Gao Jinxia Ao Chunmei Wang

BACKGROUND MicroRNAs have important roles in many biological processes. However, the role of miR-139 in healthy mammary gland remains unclear. The objective of this study was to investigate the effects of miR-139 on lactation in dairy cows. RESULTS Here, we found that miR-139 was down-regulated in mid-lactation dairy cow mammary tissues compared with mid-pregnancy tissues. Then, we prioritize...

2017
Jin Li Lei Su Ying-ying Gong Mei-lin Ding Shu-bin Hong Shuang Yu Hai-peng Xiao

Liraglutide is administered as glucagon-like peptide-1 (GLP-1) receptor agonist for diabetic patients and can protect pancreatic β-cells by inhibiting their apoptosis. MicroRNA-139-5p (miRNA-139-5p) participates in the regulation of cancer cell apoptosis. However, it is not clear whether miR-139-5p contributes to the anti-apoptotic effect of liraglutide in β-cells. The objective of the present ...

Journal: :Old Testament Essays 2019

Journal: :The British journal of ophthalmology 1971
M A Bedford C Bedotto P A Macfaul

Journal: :Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016
Cheng Pang Ming Liu Weiwei Fang Jun Guo Zhipeng Zhang Pengjie Wu Yaoguang Zhang Jianye Wang

BACKGROUND Emerging evidence suggested that microRNAs (miRNAs) play a causal role in cancer tumorigenesis. Aberrant expression of miRNA (miR)-139-5p has been observed in various types of cancers. The present study evaluated the relationship between miR-139-5p expression levels and prostate cancer (PCa), to assess the feasibility of using peripheral blood miR-139-5p as a potential non-invasive b...

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