Fluoroquinolone resistance in Staphylococcus aureus results from amino acid substitutions at particular locations in the DNA gyrase A and B subunits as well as in the topoisomerase IV A subunit and from NorA-mediated efflux. More than one resistance mechanism may be present in a single strain. Fluoroquinolone-resistant derivatives of SA-1199, a methicillin-susceptible S. aureus strain, were sel...

The newt hammerhead ribozyme is transcribed from Satellite 2 DNA, which consists of tandemly repeated units of 330 bp. However, different transcripts are synthesized in different tissues. In all somatic tissues and in testes, dimeric and multimeric RNA transcripts are generated which, to some extent, self-cleave into monomers at the hammerhead domain. In ovaries, primarily a distinct monomeric ...

The massive amounts of machine-type user equipments (UEs) will be supported in the future fifth generation (5G) networks. However, the potential large random access (RA) delay calls for a new RA scheme and for a detailed assessment of its performance. Motivated by the key idea of non-orthogonal multiple access, the non-orthogonal random access (NORA) scheme based on successive interference canc...

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