In this paper, we report the use of lead sulfide quantum dot (PbS QD) bioconjugates as near infrared (NIR) contrast agents for targeted molecular imaging with expanded emission wavelengths beyond 1000 nm. The red-shifted emission band, coupled with the small particle size, which will facilitate clearance, both afford PbS QDs unique properties for noninvasive, high resolution in vivo NIR imaging...

The portable visible and near-infrared (NIR) imaging equipment for a pre-clinical test with small animals was designed and developed in this paper. The developed equipment is composed of a CCD camera, a focusing lens, an objective lens, a NIR band pass filter and a NIR filter driving motor. An NIR ray is mainly used for imaging equipment because it has high light penetration depth in biological...

We investigate the temporal behavior of flares in the NIR and millimeter regime of Sagittarius A*, the supermassive black hole in the Galactic center, observed on 2005 July 31 at the Keck II telescope, the Very Large Telescope, and the Submillimeter Array. The time lags between a VLT NIR flare and SMA millimeter flare as well as between three quasi-simultaneous Keck NIR flares are quantified th...

The physics behind the sometimes strange effects and ‘unnatural’ appearance of near-infrared (NIR) photographs is discussed in terms of reflection, absorption and transmission of NIR radiation with the respective objects. Besides discussing how NIR cameras work, several visible and NIR photograph pairs are presented, which include vegetation, natural water, clouds, the sky, and humans. In addit...

Novel strategies that target the epidermal growth factor receptor (EGFR) have led to the clinical development of monoclonal antibodies, which treat metastatic colorectal cancer (mCRC) but only subgroups of patients with increased wild type KRAS and EGFR gene copy, respond to these agents. Furthermore, resistance to EGFR blockade inevitably occurred, making future therapy difficult. Novel bio-im...

BACKGROUND The use of near-infrared (NIR) fluorescence imaging techniques has gained great interest for early detection of cancer owing to the negligible absorption and autofluorescence of water and other intrinsic biomolecules in this region. The main aim of the present study is to synthesize and characterize novel NIR fluorescent nanoparticles based on proteinoid and PLLA for early detection ...

Near-infrared (NIR) light constitutes an integrated part of solar radiation. The principal ability to sense NIR under laboratory conditions has previously been demonstrated in fish. The availability of NIR in aquatic habitats, and thus its potential use as a cue for distinct behaviors such as orientation and detection of prey, however, depends on physical and environmental parameters. In clear ...

This review presents current research on the use of far-red to near-infrared (NIR) light treatment in various in vitro and in vivo models. Low-intensity light therapy, commonly referred to as "photobiomodulation," uses light in the far-red to near-infrared region of the spectrum (630-1000 nm) and modulates numerous cellular functions. Positive effects of NIR-light-emitting diode (LED) light tre...

Visual cognition is of significant importance in certain imaging applications, such as security and surveillance. In these applications, an important issue is to determine the cognition threshold, which is the maximum distortion level that can be applied to the images while still ensuring that enough information is conveyed to recognize the scene. The cognition task is usually studied with imag...