Prostate cancer is the most common cancer in men, with a one in eight lifetime risk and 46,690 new cases diagnosed in the UK in 2014. Between 1979 and 2011 the incidence of prostate cancer in the UK has increased by 155%. The introduction of PSA testing and systematic transrectal ultrasound (TRUS) biopsies is responsible for a significant proportion of these new diagnoses. Over the same period ...

OBJECTIVE To prospectively evaluate the efficacy and safety of periprostatic local anaesthesia (LA) during prostatic biopsy guided by transrectal ultrasonography (TRUS), as 20-65% of men report moderate to severe pain, and there is anecdotal and published evidence that periprostatic anaesthesia improves patients' tolerance. PATIENTS AND METHODS In all, 157 patients were prospectively recruite...

Prebiopsy multiparametric prostate MRI (mp-MRI), followed by transrectal ultrasound-guided (TRUS-G) target biopsies (TB) of the prostate is a key combination for the diagnosis of clinically significant prostate cancers (CSPCa), to avoid prostate cancer (PCa) overtreatment. Several techniques are available for guiding TB to the suspicious mp-MRI targets, but the simplest, cheapest, and easiest t...

THE PURPOSE Assessing the accuracy of multi parametric magnetic resonance (mp-MRI) after application of PI-RADS V2 for diagnosis of prostate cancer as comparison to pathological results of trans rectal ultra-sound (TRUS) guided biopsy. PATIENTS AND METHODS 138 prostatic lesions in 23 patients were retrospectively assessed and analyzed with Trans rectal ultra-sound (TRUS) guided biopsy results...

OBJECTIVE To improve the diagnostic efficacy of transrectal ultrasound (TRUS)-guided targeted prostatic biopsies, we have suggested the use of a new scoring system for the prediction of malignancies regarding the characteristics of focal suspicious lesions as depicted on TRUS. MATERIALS AND METHODS A total of 350 consecutive patients with or without prostate cancer who underwent targeted biop...

Objective: The decision about the treatment of localized prostate cancer (PC) depends mainly on histopathological results transrectal needle biopsy. agreement between biopsies and radical prostatectomy specimens were reported to be varying. In this study, we aimed investigate one institution’s homogenous repertory. A fair could revealed, probable strategies improve rate are discussed.
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OBJECTIVES To evaluate the use of topical glyceryl trinitrate (GTN) ointment as an adjunct to periprostatic nerve block in reducing pain associated with transrectal ultrasonography (TRUS)-guided prostatic biopsy. PATIENTS AND METHODS In all, 148 consecutive patients (mean age 67.0 years) having their first TRUS-guided biopsy were randomized to receive either 0.2% GTN ointment or placebo 10 mi...

BACKGROUND Infection after transrectal ultrasound (TRUS) guided biopsy of the prostate is a major and potentially life-threatening problem. Using antibiotic premedication can not completely eliminate infection after biopsy. OBJECTIVES We performed this study to determine the value of using povidone-iodine in prevention of post biopsy infection. PATIENTS AND METHODS Totally, 280 patients who...