BACKGROUND Dextran sodium sulfate (DSS)-induced colitis mouse model is used for research of inflammatory bowel disease. The aim of this study was to establish the adequate conditions for DSS mice model, and to find useful tool to measure inflammation. METHODS The 2.5% DSS was administered to six male C57BL/6 mice and 4% DSS to eight mice at 5 or 9 weeks of age. Each group was consisted of 6 m...

The environment in which a DSS is developed can have a significant impact on the development and satisfaction provided by the DSS. A questionnaire was sent to nonacademic TIMS members in an attemmpt to identify specific DSS environments, the capabilities provided by these DSS, and environmental factors that significantly influenced the DSS environment. This paper presents the results of this in...

The aim of the present study is to investigate the preventive effect of pioglitazone on colitis induced with dextran sulfate sodium (DSS) in rats. Twenty-four male Sprague-Dawley rats weighing 180-200 g were randomized into four groups. Rats of the 1st group received only saline and served as normal group. Colitis was induced in the remaining 3 groups by 1.5% DSS administered in drinking water ...

Despite recent progress with Decision support systems (DSS) development methodologies, a gap still exist in terms of the ability to assess the maturity of an organization with respect to its DSS development process. A need exist to be able to describe DSS development processes at a meta-level. Equally important is the ability to provide organization with prescriptions to increase the maturity o...

Aiming at sustainable development, decision-making for operation of large dams requires the assessment of complex interrelations with neighbouring environmental, economic and social subsystems. To solve this kind of highly unstructured problems often DSS are recommended. This paper presents strengths and weaknesses of DSS application in general, focusing however on large dam operation. A charac...

Decision support systems (DSS) have become increasingly important ype of computer-based information system. However, there has been limited research on management’s role, in DSS approval and administration. Because of this, the authors recently investigated eighteen decision support systems and report the findings here. The specific areas explored include motivations for developing a DSS, metho...

Traditional project management and design methods used for data processing and MIS applications are illsuited to decision support systems (DSS). The authors argue that effective management of DSS development requires: a) An explicit plan for the full development life cycle; b) Careful assignment of responsibility for DSS development; c) Appropriate user involvement and direction; and d) On-goin...

This paper critically analyses the nature and state of decision support systems (DSS) research. To provide context for the analysis, a history of DSS is presented which focuses on the evolution of a number of sub-groupings of research and practice: personal decision support systems, group support systems, negotiation support systems, intelligent decision support systems, knowledge managementbas...