Hunter, Emily, "Transcriptional Regulation of Notch target E(spl)mγ by Tramtrack69 and Putzig in Drosophila melanogaster" (2012). Abstract The Notch pathway plays an important role during development by regulating whether a cell takes on a neuronal or non-neuronal cell fate in the peripheral nervous system of Drosophila melanogaster. When Notch signaling is present in a cell, the cell is preven...

Sphingosine 1-phosphate (S1P) is a bioactive sphingolipid metabolite involved in cancer development through stimulation of cell survival, proliferation, migration, and angiogenesis. Irreversible degradation of S1P is catalyzed by S1P lyase (SPL). The human SGPL1 gene that encodes SPL maps to a region often mutated in cancers. To investigate the effect of SPL deficiency on cell survival and tran...

Background: Software product lines and Agile methods have been an effective solution for dealing with the growing complexity of software and handling competitive needs of software organizations. They also share common goals, such as improving productivity, reducing time-to-market, decreasing development costs and increasing customer satisfaction. There has been growing interest in whether the i...

The increasing complexity and cost of softwareintensive systems has led developers to seek ways of reusing software components across development projects. One approach to increasing software reusability is to develop a Software Product-line (SPL), which is a software architecture that can be reconfigured and reused across projects. Rather than developing software from scratch for a new project...

The most accepted method of secondary prophylaxis in rheumatic fever (RF) has been an injection of 1,200,000 units of benzathine penicillin G (BPG) every 4 weeks, but recurrences have been reported in some patients despite such a prophylaxis program. The WHO recommended BPG injections every 3 weeks in high risk patients and situations due to some published data in favor of inadequacy of on...

Self-paced learning (SPL) is a recently raised methodology designed through simulating the learning principle of humans/animals. A variety of SPL realization schemes have been designed for different computer vision and pattern recognition tasks, and empirically substantiated to be effective in these applications. However, the investigation on its theoretical insight is still a blank. To this is...

Unit testing is an attractive quality management tool in the software development process, however, practical obstacles make it difficult to use unit tests for performance testing. We present Stochastic Performance Logic, a formalism for expressing performance requirements, together with interpretations that facilitate performance evaluation in the unit test context. The formalism and the inter...