Active cytomegalovirus (CMV) infection was treated successfully by only CMV antibody-enriched immunoglobulin (CMV-IG) in a renal transplant recipient. CMV-IG was injected at 86 mg/kg i.v. twice a day for a total of 16 days (4 plus 12 days, interrupted by a pause of 4 days), followed by weekly i.v. injection of 86 mg/kg (7 weeks). Active CMV infection was diagnosed on the basis of DNAemia in pla...

BACKGROUND/AIMS We evaluated the proposed clinical application of the combined interpretation of host factors and viral factors in two different cytomegalovirus (CMV) co-infection models. METHODS We prospectively enrolled all human immunodeficiency virus non-infected patients with confirmed Pneumocystitis jirovecii pneumonia (PCP) and those with suspected gastrointestinal CMV disease in a ter...

abstract cytomegalovirus (cmv) is a virus that can be consider as invasive infection after transplantation or chemotherapy, long-term corticosteroid users or in immunodeficient patients such as hiv. different complications were seen in immunocompetent patients but colitis rarely occurs. the diagnosis of cmv was based on pathology by colonoscopy, positive cmv antigen and high cmv-igm titer serum...

Background. CMV causes significant morbidity in liver transplant (LT) recipients. Despite pre-existing CMV immunity, CMV-seropositive LT patients remain at risk of CMV reactivation. We aimed to investigate variables associated with CMV reactivation in CMV-seropositive LT patients. Methods. A retrospective study of CMV-seropositive LT recipients in 2007-2013 who did not receive anti-CMV prophyla...

Cytomegalovirus (CMV) is the leading cause of viral-associated congenital infections. Moreover, it can also be acquired. Between 50 to 80 percent world’s population seropositive for CMV and most clinical disease occurs in individuals previously infected with CMV. Rarely, serious infection has occurred healthy immune system. In contrast immunocompetent patients, higher morbidity mortality end or...

Background: Human cytomegalovirus (CMV) is the major complication of viral infection in immunocompromised patients. This opportunistic associated with high morbidity and mortality transplanted recipients. Objectives: The present study aimed to determine CMV burden assess clinical outcome liver recipients reactivated at Nemazi Hospital, Shiraz, Iran. Methods: retrospective examined 657 patients ...

BACKGROUND CMV is a major clinical problem in transplant recipients. Thus, it is important to use sensitive and specific diagnostic techniques to rapidly and accurately detect CMV infection and identify patients at risk of developing CMV disease. In the present study, CMV infection after liver transplantation was monitored retrospectively by two molecular biology assays - a quantitative PCR ass...

BACKGROUND Cytomegalovirus (CMV) is the most common cause of congenital infection, with increased morbidity and mortality at birth. The risk of intrauterine infection largely depends on the time of maternal infection during pregnancy. Currently, no national screening test for CMV infection is available during pregnancy in Iran. The aim of this study was to determine the seroprevalence of CMV in...

OBJECTIVE To determine the association of cytomegalovirus (CMV) viremia with CMV disease and death in patients with AIDS. DESIGN AND SETTING Prospective, observational cohort study conducted at a university hospital. METHODS A cohort of 190 subjects with AIDS who were CMV seropositive and had no history or evidence of CMV disease were longitudinally evaluated for signs and symptoms of CMV d...

BACKGROUND Cytomegalovirus (CMV) infection is associated with adverse outcomes in human immunodeficiency virus (HIV)-exposed infants. Determinants of vertical CMV transmission in the setting of maternal HIV-1 infection are not well-defined. METHODS CMV and HIV-1 levels were measured in plasma, cervical secretions, and breast milk of 147 HIV-1-infected women to define correlates of maternal CM...