Background: Histone deacetylation of tumor suppressor genes such as estrogen receptor alpha (ERα) can induce cancer, which is reversible by epi-drugs such as valproic acid (VPA). The previous result indicated that tamoxifen (TAM) induced apoptosis in hepatocellular carcinoma (HCC). This study was designed to assess the apoptotic and antiproliferative effects of VPA and TAM and also the ef...

background: the etiology of breast cancer and our understanding on the carcinogenicity of different risk factors is impotant for control programms. objective: we investigated the expression of estrogen and progesterone receptors (er, pr), and human epithelial receptor 2 (her2) overexpression and its associations, with environmental risk factors among breast cancer patients.  methods: we classif...

background: papillary thyroid carcinoma (ptc), occurs mostly in women and sex hormones may play a role in the pathogenesis and clinical course. the objective of this study was to determine the status and prevalence of estrogen and progesterone receptors in ptc with regard to age, gender, tumor size and lymph node involvement. methods: immunohistochemical stains were performed on 92 tissue block...

objective(s): this paper describes synthesispolyvinyl alcohol/caf2:er nanofibers because of  its  photoluminescence properties.materials and methods:  first, caf2:er nanocomposite synthesized with co-precipitation method. in order to prepare polyvinyl alcohol (pva)/caf2:er nanofibers, caf2:er nanocomposites were added to the polyvinyl alcohol (pva) polymer. pva/caf2:er composite nanofibers were...

Background and Objective: Since the advent of mammography screening, ductal carcinoma in situ (DCIS) of the breast has been diagnosed increasingly. In contrast to the situation in invasive breast carcinoma, there are only a few reports on androgen receptor (AR) status in DCIS and few reports on estrogen ...

Introduction: This research was aimed at examining acute responses of hormones such as growth hormone (GH), total testosterone (TT), free testosterone (FT), free fatty acid (FFA) and cortisol to resistance (R), endurance (E) and endurance-resistance (ER) exercise. Methods: The participants of this study were 10 healthy young men. R protocol included bench press, lateral pull down, leg exten...