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SUMMARY The structure of microbodies, when present, and the activities of three microbody enzymes (catalase, urate oxidase, and D-amino acid oxidase) were studied in 35 transplantable hepatomas. Microbodies are absent in hepatomas 3683, 7794A, and BRL-4-C-3. The number, size, and often the internal structures of microbodies in the other hepatomas generally reflect the growth rates and, to a cer...