BACKGROUND Little is known about differences in amounts of antioxidants or oxidative stress at different stages of knee osteoarthritis. This study investigated the relationship between concentrations of antioxidants, iron and lipid peroxidation in synovial fluid and levels of severity of primary knee osteoarthritis. MATERIALS AND METHODS From 2011 to 2013, 23 patients (mean age, 66.7 ± 7.6 ye...

Since June 1986, the University of Pennsylvania has been under contract with the Coast Guard to provide support for the Coast Guard's KSS (knowledge-based decision support systems) project. A principal output of the KSS project has been Max, a DSS shell or environment, originally designed to support modeling tasks during decision making for ship acquisition. Max is innovative in a number of way...

OBJECTIVES This systematic review and meta-analysis was conducted to determine the mid- to long-term clinical outcomes for a medial-pivot total knee replacement (TKR) system. The objectives were to synthesise available survivorship, Knee Society Scores (KSS), and reasons for revision for this system. METHODS A systematic search was conducted of two online databases to identify sources of surv...

The prognosis of progressive ophthalmoplegia in patients with large-scale mitochondrial DNA deletions is highly variable and almost unpredictable. The risk to develop cardiac involvement and sudden cardiac death is strikingly high, especially in patients with Kearns-Sayre syndrome (KSS). The most typical cardiac complications of the disease are conduction defects, which usually begin with left ...

This paper reports on some of the difficulties inherent in the integration of information from heterogeneous knowledge sources (KSs). It reviews the approaches and limitations of some recent systems, and presents example problems from an attempt to integrate two KSs in the medical terminology domain.

This paper reports on some of the difficulties inherent in the integration of information from heterogeneous knowledge sources (KSs). It reviews the approaches and limitations of some recent systems, and presents example problems from an attempt to integrate two KSs in the medical terminology domain.

Although much is known about human body vibration discomfort, there is little research data on the effects of vibration on vehicle occupant drowsiness. A laboratory experimental setup has been developed. Vibration was applied to the volunteers sitting on the vehicle seat mounted on the vibration platform. Seated volunteers were exposed to a Gaussian random vibration, with 1-15 Hz frequency band...