The best entertainment for the younger generation now is given in the form of Social Networking sites. The Online Social Networks (OSN) mainly helps an individual to connect with their friends, family and the society online in order to gather and share new experiences with others. Nowa-days, the OSNs are facing the problem of the people posting the indecent messages on any individual's wall whi...

We present a brief report on the factorization of RSA-180, currently smallest unfactored RSA number. We show that the numbers of similar size could be factored in a reasonable time at home using open source factoring software running on a few Intel Core i7 PCs.

The 180 models collected in this paper are produced by sampling and wrapping point sets on tubes. The surfaces are represented as triangulated 2-manifolds and available as stlfiles from the author’s web site at www.cs.duke.edu/ edels. Each tube is obtained by thickening a circle or a smooth torus knot, and for some we use the degrees of freedom in the thickening process to encode meaningful inf...

In applications of NMR in inhomogeneous fields, sequences based on the Carr-PurcellMeiboom-Gill (CPMG) sequence play a central role. The standard CPMG sequence consists of an initial 90° excitation pulse, followed by a long string of 180° refocusing pulses. This creates a series of echoes that decay with characteristic relaxation time T2eff. Here we present a modified sequence, the Split-180° s...

Laninamivir octanoate (LO) (Inavir; Daiichi Sankyo, Japan) is an ester prodrug of the neuraminidase inhibitor laninamivir. We previously reported that a prolonged high retention of laninamivir in mouse respiratory tissues was achieved by intranasal administration of LO. In this study, we evaluated intrapulmonary pharmacokinetics both in vivo and in vitro to investigate the potential mechanism i...

Abstract This work describes the application of a library iron(III)-salen catalysts in production biodiesel from vegetable oils. The conversion neutral soybean oil is complete within two hours at 160–180 °C with low catalyst loading (0.10 mol%). A comparative screening reveals that containing acetate as fifth ligand are most performing, and these have been conveniently used to convert acidic wa...

Rat exposure to 60% O(2) (hyper-60) or 85% O(2) (hyper-85) for 7 days confers susceptibility or tolerance, respectively, of the otherwise lethal effects of exposure to 100% O(2). The objective of this study was to determine whether activities of the antioxidant cytosolic enzyme NAD(P)H:quinone oxidoreductase 1 (NQO1) and mitochondrial complex III are differentially altered in hyper-60 and hyper...

BACKGROUND & AIMS Patients infected with hepatitis C virus (HCV) genotype 1, body weight ≥85 kg, and high baseline viral load respond poorly to standard doses of pegylated interferon (peginterferon) and ribavirin. We evaluated intensified therapy with peginterferon alfa-2a plus ribavirin. METHODS This double-blind randomized trial included HCV genotype 1-infected outpatients from hepatology c...