Centrioles are microtubule-based organelles crucial for cell division, sensing and motility. In Caenorhabditis elegans, the onset of centriole formation requires notably the proteins SAS-5 and SAS-6, which have functional equivalents across eukaryotic evolution. Whereas the molecular architecture of SAS-6 and its role in initiating centriole formation are well understood, the mechanisms by whic...

The ability to modify its own structure and/or behavior at runtime is a native feature in the development of Self-adaptive Software (SaS). In previous work, a Reference Architecture for SaS (RA4SaS), an automated process for adaptation, and a framework for decision-making were developed to assist the development of SaS. Although such initiatives have collaborated with evolution of SaS, the desi...

A user-friendly program in SAS r is proposed to perform many nonparametric smoothing and testing procedures. The nonparametric part of the program consists of resources already available on SAS and the testing part will consist of lack-of-fit tests based on smoothing ideas that will be continuously updated. Four main procedures are described for the testing part of the program: tests of a linea...

This paper discusses the conversion and consolidation of several mainframe SAS applications to UNIX using a single Web-based front end. The Web interface enables end-users to generate raw data listings and statistical summary reports from their laboratory data with no assistance from colleagues trained in SAS or the native operating system, as previously had been required when the analysis appl...

Recent advances in classical planning have used the SAS+ formalism, and several effective heuristics have been developed based on the SAS+ formalism. Comparing to the traditional STRIPS/ADL formalism, SAS+ is capable of capturing vital information such as domain transition structures and causal dependencies. In this paper, we propose a new SAS+ based incomplete planning approach. Instead of usi...

The centriole is a conserved microtubule-based organelle essential for both centrosome formation and cilium biogenesis. It has a unique 9-fold symmetry and its assembly is governed by at least five component proteins (SPD-2, ZYG-1, SAS-5, SAS-6 and SAS-4), which are recruited in a hierarchical order. Recently published structural studies of the SAS-6 N-terminal domain have greatly advanced our ...

PURPOSE To investigate the distribution of corneal and ocular spherical aberrations (SAs) in eyes with cataract in the Taiwanese population. METHODS Corneal and ocular SAs were measured in the central 6-mm optical zone using wavefront aberrometry. Axial length (AL) and keratometry (K) were also evaluated in each eye. RESULTS A total of 413 eyes in 234 patients were analyzed. The mean age of...

During the past two decades, our company Baosteel (the Baoshan Iron and Steel Corporation, Shanghai, China) has accumulated enormous data and information. Much knowledge, such as relationship, rules and patterns among these raw data, is hidden. It was very hard to reveal completely the knowledge since no advanced tools existed. Here we thank SAS Institute for providing us powerful tools to solv...

BACKGROUND Predicting subaortic stenosis (SAS) in adult Golden Retriever dogs (GRs) by evaluating them as puppies is hampered by the progressive expression of the SAS phenotype in youth. In some children who develop SAS as adults, an abnormal aortoseptal angle (AoSA) precedes development of stenosis. OBJECTIVES To determine the normal AoSA in young adult GRs using echocardiography; to assess ...

SAS® Grid Computing is a scale-out SAS® solution that enables SAS applications to better utilize I/O and compute intensive computing resources. This requires the use of high-performance shared storage (SS) that allows all servers to access the same file system. SS may be implemented via traditional NFS NAS or clustered file systems (CFS) like GPFS. This paper uses the Intel® Enterprise Edition ...