In the era of laparoscopic surgery, the best approach for common bile duct (CBD) stones remains a matter of debate. When CBD exploration was performed by laparotomy, prospective randomized trials did not show the superiority of preoperative endoscopic sphincterotomy (ES) over CBD surgery for stones.1,2 The advent of laparoscopic surgery led to a dramatic change in the approach of CBD stones tre...

BACKGROUND AND OBJECTIVES To investigate the possibility of extracting common bile duct (CBD) stones by laparoscopically inserting choledochoscope through the natural orifice of the cystic duct and a mini-incision on the CBD, and the safety of laparoscopic primary double-layer suture of the cystic duct and CBD. METHODS Laparoscopic transcystic choledochotomy and extraction of stones with prim...

The MMPs (matrix metalloproteinases) MMP-9 and -2 each possess a unique CBD (collagen-binding domain) containing three fibronectin type II-like modules. The present experiments investigated whether the contributions to ligand interactions and enzymatic activities by the CBD of MMP-9 (CBD-9) corresponded to those of CBD in MMP-2 (CBD-2). The interactions of recombinant CBD-9 with a series of col...

CC chemokine receptor 5 (CCR5) is expressed on type-1 T-helper cells, which are involved in the pathogenesis of the granulomatous lung disease chronic beryllium disease (CBD). CCR5 gene (CCR5) polymorphisms are associated with sarcoidosis severity. The present study explores associations between CCR5 polymorphisms and CBD and its disease progression. Eight CCR5 polymorphisms were genotyped in C...

Component-based development (CBD) is a name, with which software development professionals are quite familiar. There are several models which have been proposed for CBD in last few years. They contain good features but there are some improvement possibilities in them. The objective of this paper is to propose a process for CBD and to evaluate the effects of quality parameters on reusability. Th...

Our aim was to determine the effects of carotid body denervation (CBD) on the ventilatory responses to focal acidosis and ibotenic acid (IA) injections into the medullary raphe area of awake, adult goats. Multiple microtubules were chronically implanted into the midline raphe area nuclei either before or after CBD. For up to 15 days after bilateral CBD, arterial PCO2 (PaCO2) (13.3 +/- 1.9 Torr)...

CONTEXT Common bile duct (CBD) injury during cholecystectomy is a significant source of patient morbidity, but its impact on survival is unclear. OBJECTIVE To demonstrate the relation between CBD injury and survival and to identify the factors associated with improved survival among Medicare beneficiaries. DESIGN, SETTING, AND PATIENTS Retrospective study using Medicare National Claims Hist...

BACKGROUND The complete degradation of the cellulose requires the synergistic action of endo-β-glucanase, exo-β-glucanase, and β-glucosidase. But endo-β-glucanase and exo-β-glucanase can be recovered by solid-liquid separation in cellulose hydrolysis by their cellulose binding domain (CBD), however, the β-glucosidases cannot be recovered because of most β-glucosidases without the CBD, so additi...

The cannabis constituent cannabidiol (CBD) possesses anxiolytic and antipsychotic properties. We have previously shown that transmembrane domain neuregulin 1 mutant (Nrg1 TM HET) mice display altered neurobehavioural responses to the main psychoactive constituent of cannabis, Δ(9)-tetrahydrocannabinol. Here we investigated whether Nrg1 TM HET mice respond differently to CBD and whether CBD reve...