نتایج جستجو برای: ژاکت trm

تعداد نتایج: 927  

Journal: :Cell 2014
Lalit K. Beura David Masopust

Resident memory T cells (TRM) comprise a subset of nonrecirculating memory T cells that remain positioned at common portals of reinfection. These include barrier tissues such as the mucosae and skin. TRM orchestrate the initial response to pathogens re-encountered at these locales, thereby accelerating protective immune responses.

Journal: :Acta neurobiologiae experimentalis 2016
Xiaoxue Xu Feng Guo Xinze Cai Jun Yang Jiuhan Zhao Dongyu Min Qianhui Wang Liying Hao Jiqun Cai

Excessive excitation or loss of inhibitory neurotransmission has been closely related to epileptic activity. Somatostatin (SST) and Neuropeptide Y (NPY) are members of endogenous neuropeptides which are recognized as important modulator of classical neurotransmitter, distributed abundantly in mammalian central nervous system. Abnormal expression of these two neuropeptides evidenced in some epil...

2002
Daniel L. Silver Robert E. Mercer

The task rehearsal method (TRM) is introduced as an approach to life-long learning that uses the representation of previously learned tasks as a source of inductive bias. This inductive bias enables TRM to generate more accurate hypotheses for new tasks that have small sets of training examples. TRM has a knowledge retention phase during which the neural network representation of a successfully...

2016
Emma C. Reilly Kris Lambert-Emo David J. Topham

After disease resolution, a small subset of influenza specific CD8+ T cells can remain in the airways of the lung as a tissue resident memory population (TRM). These cells are critical for protection from subsequent infections with heterosubtypic influenza viruses. Although it is well established that expression of the collagen IV binding integrin alpha 1 is necessary for the retention and main...

Journal: :Blood 2015
Doris M Ponce Patrick Hilden Christen Mumaw Sean M Devlin Marissa Lubin Sergio Giralt Jenna D Goldberg Alan Hanash Katharine Hsu Robert Jenq Miguel-Angel Perales Craig Sauter Marcel R M van den Brink James W Young Renier Brentjens Nancy A Kernan Susan E Prockop Richard J O'Reilly Andromachi Scaradavou Sophie Paczesny Juliet N Barker

While cord blood transplantation (CBT) is an effective therapy for hematologic malignancies, acute graft-versus-host disease (aGVHD) is a leading cause of transplant-related mortality (TRM). We investigated if biomarkers could predict aGVHD and TRM after day 28 in CBT recipients. Day 28 samples from 113 CBT patients were analyzed. Suppressor of tumorigenicity 2 (ST2) was the only biomarker asso...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2015
Ron Shaar Lisa Tauxe

Data on the past intensity of Earth's magnetic field (paleointensity) are essential for understanding Earth's deep interior, climatic modeling, and geochronology applications, among other items. Here we demonstrate the possibility that much of available paleointensity data could be biased by instability of thermoremanent magnetization (TRM) associated with non-single-domain (SD) particles. Pale...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2014
Ali Zaid Laura K Mackay Azad Rahimpour Asolina Braun Marc Veldhoen Francis R Carbone Jonathan H Manton William R Heath Scott N Mueller

Barrier tissues such as the skin contain various populations of immune cells that contribute to protection from infections. These include recently identified tissue-resident memory T cells (TRM). In the skin, these memory CD8(+) T cells reside in the epidermis after being recruited to this site by infection or inflammation. In this study, we demonstrate prolonged persistence of epidermal TRM pr...

Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2011
W Wang D Z Xu Y F Li Y X Guan X W Sun Y B Chen R Kesari C Y Huang W Li Y Q Zhan Z W Zhou

BACKGROUND In this study, we assessed the prognostic value of the lymph node ratio (LNR), established a hypothetical tumor-ratio-metastasis (TRM) staging system and compared it with the 7th edition International Union Against Cancer pathological N (pN) and tumor-node-metastasis (TNM) system. PATIENTS AND METHODS A total of 1343 gastric cancer patients undergoing D2 resection were staged using...

Journal: :Blood 2014
Shai Izraeli Ajay Vora C Michel Zwaan James Whitlock

Children with Down syndrome are at high risk for developing B-cell precursor acute lymphoblastic leukemia (DS-ALL) associated with poor outcome due to both a high relapse rate and increased treatment-related mortality (TRM) from infections. Biologically, these heterogeneous leukemias are characterized by under-representation of the common cytogenetic subgroups of childhood ALL and overrepresent...

2013
A. Mimani C. J. Doolan

This work analyses the accuracy of numerical Time-Reversal (TR) simulations implemented using two different Time-Reversal Mirror (TRM) configurations for localising and characterising a stationary acoustic dipole source in a mean flow. The forward time evolution of the acoustic fields is simulated by means of the numerical solution of the inhomogeneous 2-D Linearised Euler Equations (LEE) with ...

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