Abstract Introduction Approximately 10,000 patients undergo cystectomy with ileal conduit diversion annually in the USA, of which ∼ 50% will subsequently develop a parastomal hernia (PSH) at 2 years. Due to knowledge gap between urostomy surgical factors and abdominal wall forces, we developed silicone ex-vivo human cadaver fascia-based model for study. Our objective was measure relationship in...

Serine palmitoyltransferase (SPT) plays the key role on catalysing formation of 3-ketodihydrosphingosine, which is first step de novo biosynthesis sphingolipids. SPT linked to many diseases including fungal infection, making it a potential therapeutic target. Thus, logical docking-based virtual screening method was used screen selective inhibitor against fungi, not human. We myriocin-similarity...

Introduction Data on the epidemiology of familial Mediterranean fever (FMF) and the prevalence of disease causing mutations among different ethnic groups and geographical regions around the world are insufficient. The prevalence of mutations that account for FMF in Turkey has been defined in the past by determining the frequency of MEFV mutations in affected individuals or in hospital-based con...

This study assesses the infrainguinal successful endovascular treatment (iSET) score’s ability to predict risk of open revascularization in patients undergoing (ER) for chronic limb-threatening ischemia (CLTI). The iSET is a score between 1 and 63. It combines components Global Vascular Guidelines evidence-based as follows: = WIfI 2 + inflow disease 4 × GLASS FP 6 IP 3 IM pedal modifier was use...

OBJECTIVE To examine whether home availability of energy-dense snack foods mediates the association between television (TV) viewing and energy-dense snack consumption among adolescents. DESIGN Cross-sectional. SETTING Secondary schools in Victoria, Australia. SUBJECTS Adolescents (n 2984) from Years 7 and 9 of secondary school completed a web-based survey, between September 2004 and July ...

PURPOSE This study aimed to evaluate stress distribution on peri-implant bone simulating the influence of platform switching in external and internal hexagon implants using three-dimensional finite element analysis. MATERIALS AND METHODS Four mathematical models of a central incisor supported by an implant were created: External Regular model (ER) with 5.0 mm × 11.5 mm external hexagon implan...