نتایج جستجو برای: 0131
تعداد نتایج: 94 فیلتر نتایج به سال:
Background: Breast cancer exhibits significant molecular, pathological, and clinical heterogeneity. Current clinicopathological evaluation is imperfect for predicting outcome, which results in overtreatment for many patients, and for others, leads to death from recurrent disease. Therefore, additional criteria are needed to better personalize care and maximize treatment effectiveness and surviv...
This paper suggests a new computational method for determining closed curves that are invariant under a given mapping. Unlike other authors, we discretize not only the curve but also the mapping itself. This allows us to avoid completely the computational difficulties connected with the numerical solution of large linear systems. The method uses simple recurrence formulas, which greatly reduce ...
BACKGROUND Incisional hernia is a frequent complication of midline laparotomy and is associated with high morbidity, decreased quality of life, and high costs. We aimed to compare the large bites suture technique with the small bites technique for fascial closure of midline laparotomy incisions. METHODS We did this prospective, multicentre, double-blind, randomised controlled trial at surgica...
BACKGROUND AND OBJECTIVES To determine the effect of a disposable automated laparoscopic suturing device, the Endo Stitch (ES) (Covidien, Mansfield, MA, USA), on hospital cost and surgical time in patients undergoing a benign total laparoscopic hysterectomy procedure compared with the use of the da Vinci surgical system (Intuitive Surgical, Sunnyvale, CA, USA) or traditional laparoscopic suturi...
There is a growing awareness, both in industry and academia, of the crucial role of formally proving the correctness of safety-critical components of systems. Most formal verification methods verify the correctness of a high-level representation of the system against a given specification. However, if one wishes to infer from such a verification the correctness of the code which runs on the act...
The paper presents approaches to the validation of optimizing compilers. The emphasis is on aggressive and architecture-targeted optimizations which try to obtain the highest performance from modern architectures, in particular EPIC-like microprocessors. Rather than verify the compiler, the approach of translation validation performs a validation check after every run of the compiler, producing...
The degree of differentiation in human cancers generally reflects the degree of malignancy, with the most undifferentiated cancer being also the highest grade and the most aggressive. High-grade serous ovarian carcinomas (HGSOC) are poorly differentiated and fast-growing malignancies. The molecular mechanisms underlying the poor differentiation of HGSOC has not been completely characterized. Ev...
TOPIC: Critical Care TYPE: Medical Student/Resident Case Reports INTRODUCTION: Bupropion is a norepinephrine/dopamine reuptake inhibitor useful in depression and smoking cessation, with seizures being its most well-known adverse effect. Here, we present case of status epilepticus secondary to overdose (OD), successfully treated intravenous lipid emulsion (ILE) therapy. CASE PRESENTATION: A 21-y...
Background Monocytes -key regulators of the innate immune response- are actively involved in pathogenesis systemic lupus erythematosus (SLE). and macrophages constitute a major cellular compartment derived from hematopoietic myeloid precursors. Monocyte-macrophage lineage cells exhibit versatile immunoregulatory, inflammatory tissue repairing capabilities play an instrumental role development A...
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