The aim of the present study was to develop Exemestane loaded polymeric nanoparticles for improved oral bioavailability of Exemestane. Exemestane loaded nanoparticles were prepared by solvent displacement method with Eudragit RL 100 and Eudragit L 100 as polymers and Pluronic® F-68 as surfactant. The influence of various formulation factors (drug: polymer ratio and concentration of surfactant) ...

The aim of the present study was to develop Exemestane loaded polymeric nanoparticles for improved oral bioavailability of Exemestane. Exemestane loaded nanoparticles were prepared by solvent displacement method with Eudragit RL 100 and Eudragit L 100 as polymers and Pluronic® F-68 as surfactant. The influence of various formulation factors (drug: polymer ratio and concentration of surfactant) ...

The aim of the present study was to develop Exemestane loaded polymeric nanoparticles for improved oral bioavailability of Exemestane. Exemestane loaded nanoparticles were prepared by solvent displacement method with Eudragit RL 100 and Eudragit L 100 as polymers and Pluronic® F-68 as surfactant. The influence of various formulation factors (drug: polymer ratio and concentration of surfactant) ...

We map substructure in three strong lensing systems having particularly good image data: the galaxy lens MG J0414+053 and the clusters SDSS J1004+411 and ACO 1689. Our method is to first reconstruct the lens as a pixelated mass map and then substract off the symmetric part (in the galaxy case) or a projected NFW (for the cluster lenses). In all three systems we find extended irregular structure...

Aims. On 28 February 2007 a new outburst of the previously known transient source XTE J1856+053 was detected with RXTE/ASM. We present here the results of an XMM-Newton (0.5–10.0 keV) Target of Opportunity observation performed on 14 March 2007, aimed at constraining the mass of the compact object in this X-ray binary and determining its main properties. Methods. The EPIC-pn camera was used in ...

Santosh Bhaskaran*, Rohan Dudhale, Jyotsana Dixit, Ajit Sahasrabuddhe and Pandit B. Vidyasagar Biophysics Laboratory, Department of Physics, University of Pune, Pune 411 007, INDIA Department of Microbiology, P.E.S. Modern College of Arts, Science and Commerce, Ganeshkhind, Pune 411 053 INDIA. $ Haffkine Institute for Training, Research and Testing, Parel, Mumbai 400 012, INDIA Department of Mi...

Why does the current wave of globalization create more public concern/opposition than previous rounds of trade liberalization? This paper identifies a key difference between globalization and trade liberalization that could be responsible for it. It is shown that while both globalization and trade liberalization create inter-sector income distribution, the former also creates intra-sector incom...