نتایج جستجو برای: 1 polymorphism
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BACKGROUND/AIMS The aim of this study was to investigate the possibility that the K469E and G241R polymorphisms in the intercellular adhesion molecule-1 (ICAM-1) gene and the C-634G polymorphism in the interleukin (IL)-6 gene are associated with endometriosis in the Korean population. METHODS The ICAM-1 gene K469E and G241R polymorphisms and the IL-6 gene C-634G polymorphism were evaluated in...
Background: Type 1 Diabetes (T1D) is a chronic and progressive autoimmune disorder. Cytokines play a critical role in the pathogenesis of T1D. Objective: IFN-¹ polymorphism was investigated in T1D and compared with normal controls. Methods: Thirty patients suffering from T1D and 40 normal controls were studied simultaneously using PCR technique. IFN- ¹ gene was evaluated at position 5’UTR...
Background Despite enormous progress in the understanding of human reproductive physiology, the underlying cause of male infertility remains undefined in about 50.0% of cases, which are referred to as idiopathic infertility and already affects about 5.0-7.0% of the general male population. Interlukin- 1 is a regulator that plays an important role in maintaining a safe environment for testes and...
Several investigations have focused on the relationship between paraoxonase-1 (PON-1) polymorphisms and the risk of polycystic ovary syndrome (PCOS); however, the result remains conflicting. To obtain a more precise estimation of the correlation between PON-1 polymorphisms [rs705379 C>T (-108C/T), rs854560 T>A (55Leu/ Met) and rs662 A>G (192Gln/Arg)] and the risk of PCOS, we performed a meta-an...
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