BACKGROUND This study compared the strength of incorporation and biocompatibility of 2 porcine-derived grafts (cross-linked and non-cross-linked) in a rat hernia model. METHODS A standardized 2 × 4 cm(2) fascial defect was created in 30 Wistar rats and repaired with either a cross-linked or a non-cross-linked graft. The rats were killed 3, 6, and 12 months later. The strength of incorporation...

Tetraspanins are integral membrane proteins involved in a variety of physiological and pathological processes. In cancer, clinical and experimental studies have reported a link between tetraspanin expression levels and metastasis. Tetraspanins play a role as organizers of multimolecular complexes in the plasma membrane. Indeed each tetraspanin associates specifically with one or a few other mem...

Although external beam radiation is an essential component to the current standard treatment of primary brain tumors, its application is limited by toxicity at doses more than 80 Gy. Recent studies have suggested that brachytherapy with liposomally encapsulated radionuclides may be of benefit, and we have reported methods to markedly increase the specific activity of rhenium-186 ((186)Re)-lipos...

Methods Seventy-three patients with FMF and 39 patients with active systemic inflammation due to autoimmune or idiopathic inflammation were evaluated in our reference center for amyloidosis. Mutations in MEFV and the SAA-1 exon 3 variants were analyzed for their contribution to AA risk. Amyloidosis was detected in all cases by congo red staining of kidney or bowel biopsy specimens and AA was cl...

K S A H A , * K N R AO , * V N S E H G A L , t S G A D I , t v K J A I N§ & A K C H A K R A BA R T Y� * Vallabhbhai Patel Chest Institute, University of Delhi, Delhi1 10 007; t Maulana A zad Medical College and associa ted LNJPN and GB Pant Hospitals , New Delhi; :j: Hindusthan Copper Complex Mines Hospital, Mosabani 832 104; § Department of Dermatology, Medical College Hospital, Roh tak 124 00...

Benzodiazepine (BZ) site ligands affect vigilance, anxiety, memory processes, muscle tone and epileptogenic propensity through modulation of neurotransmission at GABA(A) receptors containing alpha1, alpha2, alpha3 or alpha5 subunits, and may have numerous experimental and clinical applications. The ability of non-selective BZ site inverse agonists to enhance cognition, documented in animal mode...

Hong-sheng Wang 1,*, Dong-sheng Zhang 2, Lang Liu 1, Wei-bin Guo 1, Gang-wei Fan 2, KI-IL Song 3,* and Xu-feng Wang 2 1 School of Energy Engineering, Xi’an University of Science and Technology, Key Laboratory of Western Mine Exploitation and Hazard Prevention with Ministry of Education, Xi’an 710054, China; [email protected] (L.L.); [email protected] (W.-b.G.) 2 School of Mines, State Key Labora...