The aim of this study was to evaluate the potential of two probiotic preparations, containing live lactic acid bacteria (Lactococcus lactis CECT 539 and Lactobacillus casei CECT 4043) and their products of fermentation (organic acids and bacteriocins), as a replacement for antibiotics in stimulating health and growth of broiler chickens. The effects of the supplementation of both preparations (...

A 42-d trial was conducted to study the influence of 2 plant extracts on performance, digestibility, and digestive organ weights in broilers. The feeding program consisted of a starter diet until 21 d and a finisher diet until 42 d. There were 4 treatment groups: control; 10 ppm avilamycin (AB); 200 ppm essential oil extract (EOE) from oregano, cinnamon, and pepper; and 5,000 ppm Labiatae extra...

OBJECTIVE To study the impact of initiating antibiotic policy on antibiotic consumption in a neonatal intensive care unit (NICU). METHODS This retrospective study was conducted between January, 2013 and December, 2014 in a 30 bed NICU. The antibiotic policy for neonatal sepsis was initiated on January 1st, 2014. The overall antibiotic consumption (Daily Defined Dose [DDD] per 100 patient-days...

OBJECTIVE To analyse trends in antibiotic use in Dutch hospitals over the period 1997 to 2002. METHODS Data on the use of antibiotics and hospital resource indicators were obtained by distributing a questionnaire to all Dutch hospital pharmacies. Antibiotic use was expressed as the number of defined daily doses (DDD) per 100 patient-days and as DDD per 100 admissions. RESULTS Between 1997 a...

The ribosome is one of the major targets for therapeutic antibiotics; however, the rise in multidrug resistance is a growing threat to the utility of our current arsenal. The orthosomycin antibiotics evernimicin (EVN) and avilamycin (AVI) target the ribosome and do not display cross-resistance with any other classes of antibiotics, suggesting that they bind to a unique site on the ribosome and ...

488 Emerging Infectious Diseases Vol. 7, No. 3, May–June 2001 sequencing, was also used to confirm the base calls of these 100 SNPs. The visual inspection of the electropherograms and the sequencing independent method were in good agreement and indicated that 80 (91%) of 88 successful assays of the nucleotide differences were genuine. Since our initial report, we have improved our methods for o...

An experiment was carried out to evaluate the serum total protein, glucose, liver, kidney and haematological response varied levels of exogenous L-Selenomethionine (L-SeMet). Twenty four male rabbit bucks, about 10 months old were randomly allotted treatments in a completely randomized design. Blood samples collected at day 21 42 from bucks processed for haematocrit, haemoglobin, erythrocytes, ...

Large amounts of tylosin, zinc-bacitracin, and avilamycin are currently used as prophylactics in New Zealand broiler production. Avoparcin was also used from 1977 to 2000. A total of 382 enterococci were isolated from 213 fecal samples (147 individual poultry farms) using enrichment broths plated on m-Enterococcus agar lacking antimicrobials. These isolates were then examined to determine the p...

OBJECTIVES To investigate effects on surveillance results of hospital antibiotic use when WHO defined daily doses (WHO DDDs) are adjusted to doses recommended for hospitalized patients [hospital-adjusted defined daily doses (haDDDs)]. METHODS Data for antibiotic use in 2006-11 for all 22 Norwegian Health Enterprises were analysed with both WHO DDDs and haDDDs as numerators. The haDDDs were de...