Symptomatology.-In this series of 184 cases the initial symptom was as follows: Symptom No. Low backache .. Low back stiffness without pain Low back stiffness with slight pain Buttock pains .. Pain in "hips, groins or thigh" Sciatica .. .. Pain and/or swelling of knees Pain and/or swelling of ankles, heels or feet .. "Rheumatic fever" Pyrexia of unknown origin with generalized aches and pains o...

Graham Kendall Jane M Binner and Alicia M Gazely Department of Computer Science Department of Finance and Business Information The University of Nottingham The Nottingham Trent University Jubilee Campus Nottingham NG1 4BU UK Nottingham NG8 1BB UK Tel: +44 (0) 115 848 2429; + 44(0) 115 848 2416 Email: [email protected] Email; [email protected]; [email protected] Tel : +44 (0)115 846 65...

Recent observation of β decay of 115 In to the first excited level of 115 Sn with an extremely low Q β value (Q β ≤ O(1) keV) could be used to set a limit on neu-trino mass. To give restriction potentially competitive with those extracted from experiments with 3 H (≃2 eV) and 187 Re (≃15 eV), atomic mass difference between 115 In and 115 Sn and energy of the first 115 Sn level should be remeasu...

Recent observation of β decay of 115 In to the first excited level of 115 Sn with an extremely low Q β value (Q β ≤ O(1) keV) could be used to set a limit on neu-trino mass. To give restriction potentially competitive with those extracted from experiments with 3 H (≃2 eV) and 187 Re (≃15 eV), atomic mass difference between 115 In and 115 Sn and energy of the first 115 Sn level should be remeasu...

Chemotaxis is the ability of living organisms to orientate their movement towards or away a chemical substance. The term was introduced to describe cell migration observed during the early days of the development of microscopy in the XIX century. As the technology advanced, chemotactic mechanisms have turned out to be of outstanding relevance in numerous biological processes such as immune syst...

Allergic rhinitis (AR) is a common, frequently occurring disease with increasing incidences every year. House dust mite is one of the common indoor allergens that causes allergic rhinitis. So this study was aimed to evaluate the efficacy and safety of Allergopharma house dust mite vaccine in the treatment of allergic rhinitis. A case self-control method was used to compare the total symptom usi...

In some nuclear models, neutron magic numbers intersect the neutron drip line for nuclei having about 123, 187 and 264 nucleons. These masses corresponds, in GeV, to 115, 175 and 246. Reversing the argument, it can be said that a study of the neutron drip line predicts the existence of three physical scales at 115 GeV, 175 Gev and 246 Gev. Figure 1: figure 10 of [3], plus an inset of figure 20....

CC-115, a selective dual inhibitor of the mammalian target of rapamycin (mTOR) kinase and DNA-dependent protein kinase (DNA-PK), is undergoing Phase 1 clinical studies. Here we report the characterization of DNA-PK inhibitory activity of CC-115 in cancer cell lines. CC-115 inhibits auto-phosphorylation of the catalytic subunit of DNA-PK (DNA-PKcs) at the S2056 site (pDNA-PK S2056), leading to b...

Ripasudil hydrochloride hydrate (K-115), a specific Rho-associated coiled-coil containing protein kinase (ROCK) inhibitor, was the first ophthalmic solution developed for the treatment of glaucoma and ocular hypertension in Japan. Topical administration of K-115 decreased intraocular pressure (IOP) and increased outflow facility in rabbits. This study evaluated the effect of K-115 on monkey tra...