In the title mol-ecule, C(22)H(15)Cl(2)NO, the dihedral angles between the central aromatic ring and the N- and C=O-bonded rings are 43.13 (13) and 0.80 (14)°, respectively. The dihedral angle between the terminal rings is 43.15 (14)°. The major twist occurs about the C(ar)-N bond [C(ar)-C(ar)-N=C = 42.3 (4)°; ar is aromatic].

quantitative structure-activity relationship (qsar) studies of a series of substituted 3-hydroxy-pyridine-4-ones and 3-hydroxy-pyran-4-ones as antibacterial and antifungal agents against a variety of microorganisms were performed. multiple linear regression approach was used as variable selection method. the antimicrobial activities of these compounds against staphylococcus aureus, aspergilus n...