The genes which code for the 5S ribosomal RNA in the newt, Notophthalmus viridescens have been cloned and analyzed. Two types of repeating unit were detected: a major type consisting of a 120 bp coding region with a 111 bp spacer, and a minor type composed of a coding region, a pseudogene, and a 113 bp spacer. The pseudogene is a 36 bp segment which corresponds to the 3' terminal third of the 5...

Soluble extracts of the cyanobacterium Anabaena variabilis ATCC 29413 and an engineered mutant that lacks an intracellular protease cleaving after Lys and Arg (Maldener, Lockau, Cai, and Wolk, Mol. Gen, Genet. 225, 113-120 (1991)) were separated by ion exchange chromatography, and protease profiles determined using azocasein, N alpha-benzoyl-D,L-arginine-4-nitroanilide and N-carbobenzoxy-glycyl...

The antihypertensive properties of single doses of furosemide were evaluated in 113 patients. Doses over 120 mg consistently produced a fall in arterial pressure whereas smaller doses did not. Thus 20 of 22 patients (90%) who received more than 120 mg had a 26 + 6% average reduction in mean arterial pressure. The hypotensive action began in 30 to 45 minutes, the nadir of the decrease occurred b...

INTRODUCTION................................................................................... 107 I. REASONS FOR UNDERENFORCEMENT IN E-COMMERCE AND CYBERCRIME.................................................................... 109 A. Defining Underenforcement .................................................. 109 B. The Information Problem: “No Cop on the Beat” .................... 110 C. The...

We consider the problem of modeling the content structure of texts within a specific domain, in terms of the topics the texts address and the order in which these topics appear. We first present an effective knowledge-lean method for learning content models from unannotated documents, utilizing a novel adaptation of algorithms for Hidden Markov Models. We then apply our method to two complement...

A cap-containing oligonucleotide has been isolated from a T1 ribonuclease hydrolysate of total Simian Virus 40-specific late RNA and its structure has been determined as 7mG(5')ppp(5') mAmpU(m)pUp(Up,Cp)ApGp. This oligonucleotide constitutes the major 5' terminus of both late mRNA species, 16S and 19S. Assuming that viral mRNA "caps" are derived from a 5'-terminal triphosphate or diphosphate, t...

We reviewed 120 consecutive primary total hip replacements in 109 patients in whom a Freeman uncemented metal-backed component had been used. Acetabular components were used with a Freeman neck-retaining stem in one of three configurations: cemented smooth stem, uncemented smooth stem or uncemented ridged stem. After a mean follow up of 72 months (62 to 113) there were nine cases of aseptic loo...

The breast can be diffusely affected by a variety of specifi c and unique disorders, including benign disorders that are closely related to physiologic changes and infl ammatory and infectious diseases, as well as by benign and malignant tumors. The clinical manifestations include unilateral or bilateral breast enlargement with/without a palpable masses, shrinkage and breast asymmetry. Thus, kn...