Osteoarthritis (OA) is a common and dynamic disease of the joints, including the articular cartilage, underlying bones and synovium. In particular, OA is considered as the degeneration of the cartilage. Tectorigenin (Tec) is known to affect many biological processes; however, its effects on articular chondrocytes remain unclear. This study aimed to assess the effects of Tec on articular cartila...

1 Bottleneck identification locates problematic segments on a freeway corridor and meanwhile provides 2 information about the cause and characteristics of the congestion. It is a critical step in mitigating the 3 urban congestion problem. Due to the wide availability of traffic surveillance data, researchers have been 4 designing bottleneck identification algorithms based on archived traffic fl...

Multiple displacement amplification (MDA) is considered to be a conventional approach to comprehensive amplification from low input DNA. The chimeric reads generated in MDA lead to severe disruption in some studies, including those focusing on heterogeneity, structural variation, and genetic recombination. Meanwhile, the generation of by-products gives a new approach to gain insights into the r...

Bottromycins were first isolated from Streptomyces bottropensis by Waisvisz et al.1} and are especially active against Gram-positive bacteria and Mycoplasma1"3^.The complete structure of bottromycin A2 (1), the main active component of the complex, was first proposed by Nakamura et al. in 1966 as a linear peptide4'5), but the structure was revised in 1976 by Takahashi et al.6) to a partly cycli...

The title compound, C10H10BrClN2OS, adopts a trans-cis conformation with respect to the position of the 3-chloro-propanoyl and 4-bromo-phenyl groups, respectively, against the thiono C=S bond across their C-N bonds. The benzene ring makes a dihedral angle of 9.55 (16)° with the N2CS thio-urea moiety. Intra-molecular N-H⋯O and C-H⋯S hydrogen bonds occur. In the crystal, mol-ecules are linked int...

Zeolites with a small pore structure are considered as the most efficient catalysts to satisfy increasingly stringent emission requirement for diesel vehicles. Since molecular size of NO is comparable small-pore zeolites, formation ammonium and sulphates during selective catalytic reduction NOx NH3, limits mass transportation become major obstacle that reduces its performance. In this study, in...